Molecular markers of myeloid-derived suppressor cells and their functional role for homing and in disease models in mice
IN Eckert - 2023 - opus.bibliothek.uni-wuerzburg.de
… bone marrow cells for 3 days followed by the activation with LPS and IFN-γ for 16 h, which
results in iNOS expression… -1 was co-expressed with CD62L and VLA-4, but not with lymph …
results in iNOS expression… -1 was co-expressed with CD62L and VLA-4, but not with lymph …
[HTML][HTML] CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity
JC Gutjahr, E Bayer, X Yu, JM Laufer, JP Höpner… - …, 2021 - ncbi.nlm.nih.gov
… VLA-4, a CD49d/CD29 heterodimer, are important factors in progenitor cell adhesion in bone
… Notably, we did not observe CD44-VLA-4 inside-out activation in normal CD34 + mobilized …
… Notably, we did not observe CD44-VLA-4 inside-out activation in normal CD34 + mobilized …
Physiological cues involved in the regulation of adhesion mechanisms in hematopoietic stem cell fate decision
R Kulkarni, V Kale - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
… Specifically, α4β1 (VLA-4), α5β1 (VLA-5), and αLβ2 (LFA-1) … that the CD34 + cord blood
HSCs expressing L-selectin form … the association of CXCR4 with the integrins VLA-4 and VLA-5. …
HSCs expressing L-selectin form … the association of CXCR4 with the integrins VLA-4 and VLA-5. …
The downregulated membrane expression of CD18 in CD34+ cells defines a primitive population of human hematopoietic stem cells
C Mesa-Núñez, D Leon-Rico, M Aldea… - Stem Cell Research & …, 2020 - Springer
… of human hematopoietic stem and progenitor cells (HSPCs) from cord blood (CB), bone marrow
(BM… LFA-1 is mainly involved in the leukocyte adhesion cascade and also in the immune …
(BM… LFA-1 is mainly involved in the leukocyte adhesion cascade and also in the immune …
Hematopoietic multipotent progenitors and plasma cells: neighbors or roommates in the mouse bone marrow ecosystem?
… -biased CD34+ precursors expressing more frequently LFA-1 and L-selectin and expressing
… receptors and adhesion molecules expressed by the progenitor cells, such as VLA-4, VLA-5…
… receptors and adhesion molecules expressed by the progenitor cells, such as VLA-4, VLA-5…
Leukocyte movement during immune responses
E Vadillo - Cell Movement in Health and Disease, 2022 - Elsevier
… the bone marrow (BM) to PB also occur. Antigen-presenting … the HEVs and employ L-selectin
to interact with CD34 and Gly-… of LFA-1 and VLA-4, resulting in firm arrest. Effector CD8 + T …
to interact with CD34 and Gly-… of LFA-1 and VLA-4, resulting in firm arrest. Effector CD8 + T …
Biology of Hematopoietic Stem Cells in the Adult
R Haddad, F Pflumio… - Stem Cell Biology and …, 2022 - api.taylorfrancis.com
… gene deletion in mice uncovered the contribution of VLA-4 in … of CD10 with upregulation
of L-selectin. Nat Immunol. 2012;… The chemokine SDF-1 activates the integrins LFA-1, VLA-4, …
of L-selectin. Nat Immunol. 2012;… The chemokine SDF-1 activates the integrins LFA-1, VLA-4, …
Oncogenic deregulation of cell adhesion molecules in leukemia
R Windisch, N Pirschtat, C Kellner, L Chen-Wichmann… - Cancers, 2019 - mdpi.com
… -1 and L-selectin were diminished compared with control cells, … VLA-4-dependent adhesion
of hematopoietic progenitor cell … cell adhesion molecules PSGL-1, LFA-1, CD44, and VLA-4 …
of hematopoietic progenitor cell … cell adhesion molecules PSGL-1, LFA-1, CD44, and VLA-4 …
[HTML][HTML] Development of VLA4 and CXCR4 Antagonists for the Mobilization of Hematopoietic Stem and Progenitor Cells
PG Ruminski, MP Rettig, JF DiPersio - Biomolecules, 2024 - mdpi.com
… a sufficient number of CD34 + HSPCs from the … bone marrow microenvironment. Preclinical
and/or clinical studies have demonstrated that disrupting the interaction of CXCR4 or VLA-4 …
and/or clinical studies have demonstrated that disrupting the interaction of CXCR4 or VLA-4 …
In vitro Imaging and Characterization of Hematopoietic Stem Cells on E/P Selectin Surfaces
A Rakhmatulina - 2023 - repository.kaust.edu.sa
… come into contact with the endothelial lining of the bone … α4β7, VLA-4, and LFA-1) bind
strongly to immunoglobulin cell … -1 activate the binding of CD34+ cell binding to the extracellular …
strongly to immunoglobulin cell … -1 activate the binding of CD34+ cell binding to the extracellular …