… observed between some MAPKs. We also describe the basic signaling properties of MAPKs
(… It seems that the differential affinity of substrates for MAPKs could account for the kinetics …

… for other MAPKKs and MAPKs (eg, MEK1/2, or p38α/β [53,54]), but not in the JNK cascade,
in which the small differential effects are mainly due to distinct activities and regulation of the …

… MAPK/ERK pathway in morphogenesis are emerging [5,6,7,8], and we recently reported the
activation of MAPK/… However, the full spectrum of MAPK/ERK functions at the cellular level, …

… Importantly, several studies have proposed that JNK isoforms exhibit differential roles in β-cell
apoptosis depending on the stimuli. JNK3 was found to have antiapoptotic properties in …

… Are MAPKAPKs simple downstream servants of MAPKs that merely … of MAPK signals, provide
feedback control, and even regulate the stability and subcellular localization of the MAPKs, …

… The differential regulation of c-JUN is thought to be responsible for these effects [217]. In
MEFs, JNK loss in combination with the double knockout of TP53 (TP53–/–) results in MET, as …

… factors may allow us to develop a regulation network to increase our knowledge of … MAPK
pathway activation and responses under HMs and mainly focused on the specificity of MAPK …

… In this literature review, we recapitulated the multifaceted MAPK/ERK signaling regulations,
… possibility of MAPK/ERK signaling as a critical mechanism underlying the vastly differential …

… regulate all aspects of life and are frequently altered in disease. Here, we focus on the role
of MAPK … We briefly discuss new findings in the extracellular signaling-regulated kinase (ERK…

… is regulated also by the MAPK signaling pathways under stress conditions. Three conventional
MAPK signaling pathways (ERKs, JNKs, and p38-MAPKs… p38-MAPKs stimulate apoptosis …