… – hyperpolarised (HP) gas MRI with inhaled 3 He and 129 Xe – a method for functional and
microstructural imaging of the lung … which can be probed by HP gas diffusion-weighted MRI. …

… The ability of hyperpolarized gases to evaluate physical diffusion of gases within the lung …
The use of ADCs of hyperpolarized noble gases for ventilation MRI may become a standard of …

… images. This approach provides a method to generate four nonzero b-values for diffusion-weighted
hyperpolarized gas MRI … static-ventilation and multi-b diffusion-weighted scans into a …

… of the previous study using HP gas MRI.17, 35 A recent study on explanted lungs showed
that HP 129 Xe DWI could quantify the severity of lung parenchyma destruction, and the …

… The dynamics of xenon gas diffusion over the entire lung was also investigated by measuring
the signal intensity variations between three regions of interest, including the left and right …

… Driehuys is a founder of Polarean Imaging, a company that is working to commercialize
hyperpolarized 129 Xe gas MRI. None of the other authors has any conflicts of interest, financial …

… Respiratory and cardiac motion further complicate MRI of the lung. MRI of inhaled
hyperpolarized gases, in contrast, provides a means for assessment of lung microstructure and …

… functional and structural imaging of the lungs. Hyperpolarized gas diffusion-weighted (DW)
MRI … noninvasive and quantitative assessment of microstructural acinar changes in the lungs. …

… HP gas MRI for detection of early CF lung disease and following the effects of interventions.
The typical HP gas imaging workflow is described, along with a discussion of image analysis …

… and abnormal infant lung specimens at ages 0–16 … gas diffusion MRI in the airspace size
regime of infant lungs. This ex vivo study is an important proof-of-concept for gas diffusion MRI …