How nanoparticles transform single molecule measurements into quantitative sensors

Y Wu, D Bennett, RD Tilley, JJ Gooding - Advanced Materials, 2020 - Wiley Online Library
… corresponds to a detected magnetic nanoparticle and thus a … a digital single molecule sensor
for multiplexed detection of a … a nanoparticle address the issue of lifetime of biomolecular

A critical review: Recent advances in “digital” biomolecule detection with single copy sensitivity

H Liu, Y Lei - Biosensors and Bioelectronics, 2021 - Elsevier
… about digital detection of biomolecules with potential single copy … binding with one capture
antibodies labeled magnetic bead, … can precisely localize the nanoparticles and recognize the …

Critical Review: digital resolution biomolecular sensing for diagnostics and life science research

Q Huang, N Li, H Zhang, C Che, F Sun, Y Xiong… - Lab on a Chip, 2020 - pubs.rsc.org
… In this work, PSA antigens are first captured by detection antibodies on both magnetic … of
SPRI hinders the ability to discern individual nanoparticles especially when they are densely …

Magnetic nanoparticles in microfluidic and sensing: From transport to detection

S Khizar, H Ben Halima, NM Ahmad, N Zine… - …, 2020 - Wiley Online Library
Magnetic microbeads have been used to characterize many biomolecular interactions for the
detection of nucleic acid (… A digital microfluidic (DMF) platform based on the manipulation of …

Magnetic nanoparticle-based molecular communication in microfluidic environments

W Wicke, A Ahmadzadeh, V Jamali… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
magnetic nanoparticles for the design of molecular communication systems. In particular, we
consider a magnetic nanoparticle-… channel where an external magnetic field is employed to …

Investigating the effect of magnetic dipole–dipole interaction on magnetic particle spectroscopy: implications for magnetic nanoparticle-based bioassays and magnetic …

K Wu, D Su, R Saha, J Liu… - Journal of Physics D …, 2019 - iopscience.iop.org
… to digital acquisition card (DAQ) and instrumental amplifiers (IAs), analog to digital convertor
(… to drive coils to generate two sinusoidal magnetic fields, one with high frequency but low …

Advances in the application of magnetic nanoparticles for sensing

L Gloag, M Mehdipour, D Chen, RD Tilley… - Advanced …, 2019 - Wiley Online Library
… in a sample must have the same magnetic, electrical, optical and surface properties to
achieve quantitative detection, especially as we approach the single molecule limit of detection. …

Single-molecule biosensors: Recent advances and applications

N Akkilic, S Geschwindner, F Höök - Biosensors and Bioelectronics, 2020 - Elsevier
… , highlighting nanoparticle-amplified assays, digital platforms … , single-molecule detection
of biomolecular interactions, can … such as gold, silver or magnetic silica nanotubes. SERS is …

Advances in Optical Single‐Molecule Detection: En Route to Supersensitive Bioaffinity Assays

Z Farka, MJ Mickert, M Pastucha… - Angewandte Chemie …, 2020 - Wiley Online Library
… background on single-molecule—or better digital—assays to … fluorescent molecules, and
nanoparticles. Through the choice … FCS can be exploited to follow molecular interactions with …

[HTML][HTML] Microfluidic synthesis, control, and sensing of magnetic nanoparticles: A review

R Abedini-Nassab, M Pouryosef Miandoab, M Şaşmaz - Micromachines, 2021 - mdpi.com
… invented for the detection and magnetic measurement of magnetic nanoparticles and
magnetically … , the GMR sensor detects magnetic nanoparticle tags of the biomolecules of interest. …