… of hemoglobin N-terminal valine adducts (added mass, 106.042 Da) in the blood of human
… The resulting mass spectrometry data were processed using Proteome Discover. We utilized …

… have facilitated the discovery of unknown human exposures to … the Hb adduct levels by
HRMS in the blood available from … an adduct detected to N-terminal valine in Hb in human blood …

… Hb adducts of N-terminal valine (30–150 pmol/g Hb) correspond to 5–25 adducted Hb chains
per 10 7 Hb chains in a human blood … recently identified 4-hydroxybenzyl Hb adduct may …

… and blood metabolites are short term exposure markers. Stable hemoglobin adducts are …
review of the progress made in regard to albumin and hemoglobin adduct determinations. …

… the N-terminal Valine Hb adduct formation via the FIRE method. Semiquantitative dose–response
curves of blood … of analysis, making this method unsuitable for discovery experiments. …

… If the investigator’s aim is to discover biomarkers of exposure, a … N-(4-hydroxybenzyl)valine,
postulated to have arisen from either 4-quinone methide, which could form the valine adduct …

… valine residues in Hb formed adducts … valine residues in the Hb sequence. However, several
reports have suggested that many compounds are preferably bound to the N-terminus of Hb…

… Blood samples were analyzed using the adduct FIRE procedure [35]. The principle for this
procedure is that adducts on N-… Whole blood (250 μL) was alkalized with 1 M KHCO 3 (20 μL), …

… of the W car -adduct will enable estimation of blood methomyl … and valine residues in Hb
formed carbamylated adducts with … residue in Hb formed carbamylated adducts with thiofanox (…

… human blood samples using the FIRE procedure to screen for adducts to N-terminal valine
in Hb found an unknown adduct … Alternative Formation of N-(4-hydroxybenzyl)valine Adducts …