… , and microglia, with neurons under physiological conditions. … disrupt glial function, and how
this disruption might impair glia-neuron metabolic crosstalk and ultimately promote cognitive …

… -neuron lactate shuttle (ANLS), interrupt the balance in energy metabolism, and resulting in
cognitive function, … against the disorder of energy metabolism caused by aluminum in mice. …

… In AD, neurovascular system impairment leads to reduced brain perfusion and disruption to
… are used to ameliorate cognitive function by enhancing the energy metabolism level in AD. …

… Brain energy metabolism declines subtly during ageing and this … Local interneuron dysfunction
disrupts synchronization between remote neuronal networks and across brain regions 31,…

… regulating neural circuit function has received little attention. … hypothesized to drive metabolic
and cognitive decline [26]. In … other pathological features including disrupted cholinergic, …

… , and on its neurodegenerative-related disruption. We sought … to increased vulnerability
to cognitive decline. Thus, in light … of vulnerable neuronal circuits in AD [205]. Mitochondrial …

… cognitive consequences of disrupted energy metabolism. Thus “bioenergetic stress” drives
systemic inflammation-induced dysfunction. … LPS-induced cognitive impairment in ME7 mice …

… the brain, disrupting neural circuits involved in cognition and … and which directly impaired
cognitive function, including … cognitive impairment are associated with metabolic disorders…

… and behavioral deficits in LgDel mice. Our results provide new mechanistic insight and a
potential therapeutic approach for disrupted cortical circuit development in 22q11DS. …

… metabolic diseases cause cognitive impairment it may be possible to better understand and
extend how central metabolic changes affect cognitive function … can disrupt the function of …