Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood

S Kariotis, E Jammeh, EM Swietlik, JA Pickworth… - Nature …, 2021 - nature.com
… 13 studies have described diagnostic and prognostic biomarkers that add to our increasing
… into multiple distinct transcriptomic subgroups that associate with different survival properties…

Identification of common signatures in idiopathic pulmonary fibrosis and lung cancer using gene expression modeling

D Leng, J Yi, M Xiang, H Zhao, Y Zhang - BMC cancer, 2020 - Springer
… The gene expression profiles of patients with lung disorders were distinct from those of the
healthy controls, and 11,926 genes were significantly differentially expressed with P < 0.05 (…

Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

Z Aversa, EJ Atkinson, EM Carmona, TA White… - Respiratory …, 2023 - Springer
… in the current study was based on diverse components of the SASP commonly observed in
cell… While individual components of our biomarker panel are certainly not unique to senescent …

Decreased peak expiratory flow rate associated with mortality in idiopathic pulmonary fibrosis: A preliminary report

K Fujita, H Ohkubo, A Nakano… - Chronic Respiratory …, 2022 - journals.sagepub.com
… In conclusion, a decrease in PEFR after 6 months could be a novel and useful prognostic
Where there are more than one item, you can scroll through each tab to see each separate

Biomarkers and early treatment of idiopathic pulmonary fibrosis

JA Kropski - The Lancet Respiratory Medicine, 2019 - thelancet.com
… The study population was unique compared with other idiopathic pulmonary fibrosis trials …
in idiopathic pulmonary fibrosis trials seems necessary. Currently recognised prognostic

Integrative analysis of lung molecular signatures reveals key drivers of systemic sclerosis-associated interstitial lung disease

SM Jung, KS Park, KJ Kim - Annals of the Rheumatic Diseases, 2022 - ard.bmj.com
… Although SSc-ILD shares many pathogenic features with idiopathic pulmonary fibrosis (IPF), …
common and distinct pathways involved in the four disease groups. The composition of key …

Progression of fibrosing interstitial lung disease

AW Wong, CJ Ryerson, SA Guler - Respiratory research, 2020 - Springer
… medications in patients with idiopathic pulmonary fibrosis (IPF) and … important given the
worse prognosis in IPF compared to … effect in pulmonary fibrosis caused by a variety of different

Standardised 3D-CT lung volumes for patients with idiopathic pulmonary fibrosis

Y Tanaka, Y Suzuki, H Hasegawa, K Yokomura… - Respiratory …, 2022 - Springer
… images, providing accurate lung volume (LV) measurements in different lung lobes. … 3D-CT
LV of the lower lobes had no prognostic impact, while the standardised 3D-CT LV of the …

Pleuroparenchymal fibroelastosis. A review of clinical, radiological, and pathological characteristics

F Chua, SR Desai, AG Nicholson… - Annals of the …, 2019 - atsjournals.org
idiopathic pulmonary fibrosis, patients with chronic obstructive … a negative prognostic impact
specifically attributable to UIP (… PPFE and a separate fibrotic lung disease such as UIP fare …

From cigarette smoking to Chronic Obstructive Pulmonary Disease or Idiopathic Pulmonary Fibrosis. Why?

D Biondini - 2019 - research.unipd.it
… Moreover, we also explored whether different lung tissue inflammatory profiles may impact
on the response to Pirfenidone treatment, which exerts also an anti-inflammatory effect. Finally…