… ), which are fibrils of different morphology mainly composed of … -related cell survival and
differentiation, but also neuronal … acting as a docking site for ShcC. Once bound and activated, …

… NPCs differentiate into neurons which migrate along defined … to recruit other signaling proteins,
while ShcC and ShcD contain … distinct functions of each homolog, and how their functions …

… ShcB and ShcC proteins are expressed only … proteins share a similar structure they have
different functions. p52ShcA is involved predominantly in cell proliferation, p66ShcA has a role …

… neuronal cell line hybrid between murine neuroblastoma cells and rat dorsal root ganglia
(DRG) … RNA-Seq experiments performed using different samples. Changes observed in genes …

… plays a role in neurogenesis and neuroblastoma progres… ) have different target kinase
selectivity, and (iii) cause a different … for hyperphosphorylation of ShcC in neuroblastoma cell lines. …

… that Rho GEFs have different functions at different stages of … Shc has a clear role in promoting
the differentiation of matrix- … GEF aberrantly expressed by neuroblastomas and roughly half …

… of investigated tumors were distinguished: choroid plexus tumors… as a negative prognostic
marker in neuroblastoma [48,49]. … (at the 5% level) difference in the level of TrkB between CNS …

… regulation of oligodendrocyte differentiation and myelination, … of Rai expression in
neuroblastomas and in brain tumors has … that different stress stimuli regulate Rai protein …

… as cell proliferation, migration, differentiation and survival. TKs can be … a unique function in
human ALK-mediated transformation. … neuroblastoma patient samples. Involvement of ALK in …

… protein assay kit (Beyotime, Nantong, China), the protein … gel electrophoresis was used to
separate proteins, which were … Although there was no significant statistical difference between …