Role of microRNA in muscle regeneration and diseases related to muscle dysfunction in atrophy, cachexia, osteoporosis, and osteoarthritis

J Brzeszczyńska, F Brzeszczyński… - Bone & joint …, 2020 - boneandjoint.org.uk
… Impaired musculoskeletal homeostasis leads to distinct muscle atrophies. Understanding …
miRNA expression in muscle of septic ICU patients, which reported an increase in primary miR-…

miRNA profiling for early detection and treatment of duchenne muscular dystrophy

HC Hrach, M Mangone - International journal of molecular sciences, 2019 - mdpi.com
… genes are located in clusters, transcribed with unique promoters, or found in intronic regions
… of human neuromuscular diseases [6,7]. For example, changes in miRNA expression have …

MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies

JE Parkes, A Thoma, AP Lightfoot, PJ Day, H Chinoy… - BMC rheumatology, 2020 - Springer
… are heterogeneous autoimmune conditions of skeletal muscle inflammation and weakness.
… for IIM due to the delay to IIM diagnosis, all of which may alter mRNA and miRNA expression. …

Muscle weakness in myositis: MicroRNA‐mediated dystrophin reduction in a myositis mouse model and human muscle biopsies

TB Kinder, CR Heier, CB Tully… - Arthritis & …, 2020 - Wiley Online Library
… and miRNA expression and histologic features in the muscle tissue… and other muscle disorders,
in particular, Duchenne muscular … Previously, we described 2 distinct sets of microRNAs (…

Uniform sarcolemmal dystrophin expression is required to prevent extracellular microRNA release and improve dystrophic pathology

TLE van Westering, Y Lomonosova… - … and Muscle, 2020 - Wiley Online Library
muscular dystrophy (DMD) is a fatal muscle-wasting disorder … To this end, miRNA expression
was measured by RT-qPCR in … distinct relationships exist between dystrophin expression in …

[PDF][PDF] MicroRNAs and HDAC4 protein expression in the skeletal muscle of ALS patients

V Pegoraro, R Marozzo, C Angelini - Clinical neuropathology, 2020 - researchgate.net
… individuals with no neuromuscular disorders were selected. … Microscopic atrophy grading
was performed by two distinct … tion, miRNA expression levels were normalized on miRNA 39-3p …

microRNA dysregulation in neurodegenerative diseases: A systematic review

CA Juźwik, SS Drake, Y Zhang, N Paradis-Isler… - Progress in …, 2019 - Elsevier
diseases. We recorded miRNA expression from articles that report miRNA … miRNAs, we
identified roles for each miRNA in regulating distinct neuronal and immune aspects of disease. A …

Human miRNA miR-675 inhibits DUX4 expression and may be exploited as a potential treatment for Facioscapulohumeral muscular dystrophy

NY Saad, M Al-Kharsan, SE Garwick-Coppens… - Nature …, 2021 - nature.com
… , there were two practical problems with this strategy: (i) there were no microRNAs known
to … individual microRNA expression plasmids in an increasing luciferase DUX4 reporter:miRNA

Metabolic, fibrotic and splicing pathways are all altered in Emery-Dreifuss muscular dystrophy spectrum patients to differing degrees

JI de Las Heras, V Todorow… - Human Molecular …, 2023 - academic.oup.com
… Furthermore, the segregation of specific gene changes into distinct groups that appear to …
extracted the DE genes for each of the neuromuscular diseases. We then checked our data for …

Circulating microRNAs as diagnostic biomarkers for motor neuron disease

L Wang, L Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
… the characteristics of distinct differential expression, sensitive … sclerosis is a progressive
paralytic disorder characterized by … There are few studies on differential miRNA expression in …