Autoradiographic labelling of 5-HT3 receptors in the hemi-parkinsonian rat brain

C Kwan, C Levesque, D Bedard, I Frouni… - Neuroscience …, 2022 - Elsevier
binding with the highly selective antagonist [ 3 H]GR65630 in 6-… 3A-3H, [ 3 H]GR65630
binding in the ipsilateral hemisphere … 6-OHDA rat at the post-mortem level. Taken together, these …

Distribution of 5-HT receptors in the central nervous system: an update

MT Vilaró, R Cortés, G Mengod, D Hoyer - Handbook of behavioral …, 2020 - Elsevier
… Receptor binding and mRNA are barely detectable in basal ganglia … the human brain, the
distribution of 5-HT 1D receptors was then defined as the fraction of [ 3 H]-sumatriptan binding

5-HT3 receptors in GtoPdb v.2023.3

NM Barnes, TG Hales, SCR Lummis… - IUPHAR/BPS Guide …, 2023 - journals.ed.ac.uk
… , but generally has only a modest effect upon the apparent affinity of agonists, or the affinity
of antagonists ([19], but see [44, 33, 38]) which may be explained by the orthosteric binding

5-HT3 receptors in GtoPdb v.2021.3

NM Barnes, TG Hales, SCR Lummis… - IUPHAR/BPS Guide …, 2021 - journals.ed.ac.uk
… , but generally has only a modest effect upon the apparent affinity of agonists, or the affinity
of antagonists ([19], but see [44, 33, 38]) which may be explained by the orthosteric binding

Synthesis and development of indole based 5-ht3 receptor antagonists as anti-emetic drugs in oncology: an update

JL Rivera-Fonseca, N González-Rivas… - Current Medicinal …, 2021 - ingentaconnect.com
GR-65630 binding was found in homogenates of the area postrema, as well as high levels
of binding in … , BJ; Tyers, MB Binding of the 5HT3 ligand, [3H]GR65630, to rat area postrema, …

Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT3 receptor binding in the NTS in …

WT Donnelly, RL Haynes, KG Commons… - Experimental …, 2020 - Elsevier
… For each brain, 3 H GR65630 binding was measured at 3 different brainstem levels within …
change the relative distribution of 5-HT 3 binding within the NTS: 5-HT 3 binding was greatest …

Radioligands for Serotonin Receptors and Transporter PET Imaging

DJ Kim, C Huang - Hybrid PET/MR Neuroimaging: A Comprehensive …, 2022 - Springer
… Antagonistic radioligands also bind to the specific receptor of … the blood-brain barrier (BBB)
and specific binding to the target … , and regional brain distribution findings displayed similar …

[图书][B] Towards therapies for Parkinson's Disease: treatment-related complications and animal models

C Kwan - 2022 - search.proquest.com
… by prolonging its half-life and its delivery to the brain 186. COMT inhibitors are often … binding
studies have revealed increased striatal D2 receptor binding sites in the post-mortem brains

[图书][B] Stereological investigation of serotonin type 3 receptors in the substantia nigra and dorsal raphe nucleus in the rat

S Belliveau - 2019 - search.proquest.com
… Here, we determine the quantitative distribution of 5-HT3 … Des études antérieures ont montré
la distribution du récepteur 5-… déterminons quantitativement la distribution des récepteurs 5-…

Structural and behavioural signatures of enhanced plasticity resulting from a single dose of the psychedelic drug DOI

M Šabanović - 2022 - ora.ox.ac.uk
Brain function involves coordinated integration and segregation of information over networks
linking spatially distributed specialized brain areas. Structural brain networks refer to the …