Investigation of biomarkers and handling strategy of erlotinib-induced skin rash in rats

I Julian, T Iwamoto - Biological and Pharmaceutical Bulletin, 2021 - jstage.jst.go.jp
… on rash development were observed. We comprehensively investigated erlotinib-induced
skin rash biomarkers … Erlotinib is distributed into peripheral organs such as bone marrow and …

Correlation of skin rash and overall survival in patients with pancreatic cancer treated with gemcitabine and erlotinib–results from a non-interventional multi-center …

CB Westphalen, T Kukiolka, B Garlipp, L Hahn… - BMC cancer, 2020 - Springer
… with metastatic pancreatic carcinoma were treated with gemcitabine/erlotinib (Tarceva®)
based on the decision of the treating physician. Data were collected before the initiation of the …

[HTML][HTML] Retrospective analysis of skin toxicity in patients under anti-EGFR tyrosine kinase inhibitors: our experience in lung cancer

MC Annunziata, M Ferrillo, E Cinelli… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
… It is generally distributed in the seborrheic areas, where … one of them developed a rash (50%
of total patients), but we … reported in three female patients treated with erlotinib, and one of …

Comparison of Plasma Metabolites From Patients With Non-Small Cell Lung Cancer by Erlotinib Treatment and Skin Rash

WK Lee, J Myong, E Kwag, Y Shin… - Integrative Cancer …, 2023 - journals.sagepub.com
… plasma metabolites that increased after erlotinib treatment in patients who had a skin rash.
Three patients developed a skin rash after receiving erlotinib treatment, and their metabolite …

[HTML][HTML] Acute generalized exanthematous pustulosis caused by erlotinib in a patient with lung cancer

N Komiya, K Takahashi, G Kato, M Kubota… - … Reports in Oncology, 2021 - karger.com
… base that are mainly distributed in the trunk and … adverse skin effects: acneiform rash (63%),
dry skin (7.7%), pruritus (3.8%), and paronychia (6.0%) [13]. Erlotinib-related acneiform rash

Cutaneous leukocytoclastic vasculitis associated with erlotinib treatment: A case report and review of the literature

GL Fekete, L Fekete - Experimental and therapeutic …, 2019 - spandidos-publications.com
… , became more distributed and were associated with moderate pruritus and pain. The …
erlotinib treatment. Cutaneous side effects of protein kinase inhibitors, such as maculopapular rash

[PDF][PDF] Tyrosine Kinase Inhibitor (Erlotinib)-induced Papulopustular Rash

R Gupta, S Mahajan, M Kaur - … Current Trends in Diagnosis & Treatment, 2022 - ctdt.co.in
… Acneiform rash during lung cancer therapy with erlotinib (Tarceva®). Poste py Dermat
Alergol … Erlotinib-induced skin rash in patients with non-small-cell lung cancer: Pathogenesis, …

Eye, hepatobiliary, and renal disorders of erlotinib in patients with non-small-cell lung cancer: A meta-analysis

HD Choi, MJ Chang - PloS one, 2020 - journals.plos.org
… That is, erlotinib-related skin rash and diarrhea have been evaluated carefully based on the
clinical application and studies and how to manage about the adverse events are also well …

Therapeutic drug monitoring of erlotinib in non-small cell lung carcinoma: A case study

A Catalán-Latorre, M Sureda… - Therapeutic Drug …, 2021 - journals.lww.com
treatment, erlotinib serum concentrations were measured, and the dose was accordingly
adjusted. The erlotinib dose required to reduce toxicity (rash … were V (volume of distribution, L), …

Epidermal growth factor receptor tyrosine kinase inhibitor erlotinib induces dry skin via decreased in aquaporin-3 expression

N Ikarashi, M Kaneko, T Watanabe, R Kon, M Yoshino… - Biomolecules, 2020 - mdpi.com
… many patients complain of an acneiform rash or dry skin during … using erlotinib to clarify the
mechanism of dry skin caused by … levels and distribution of aquaporin (AQP) in mouse skin. …