… dephosphorylation of cyclase-associated protein 1 by antagonistic signaling through cyclin-dependent kinase 5 and cAMP are critical for the protein functions in actin …

H Zhang, A Ramsey, Y Xiao, U Karki… - … and cellular biology, 2020 - Taylor & Francis
… In dissecting further phosphoregulatory cell signals for CAP1… the phosphomimetic and the
nonphosphorylatable mutant of … ), an activator of protein kinase C that we previously found to …

[HTML][HTML] Ca2+ Signaling and Src Functions in Tumor Cells

A Villalobo - Biomolecules, 2023 - mdpi.com
… by a unique domain specific to each Src-family kinase (SFK) … the myristoylated peptide by
protein kinase C (PKC) at both … , we prepared phosphomimetic CaM mutants by substituting …

Defining the Molecular Mechanisms that Govern Par-3 Mediated Polarization of the Par-Complex

R Holly - 2020 - scholarsbank.uoregon.edu
… polarity is the protein kinase, atypical Protein Kinase C (aPKC)… The Protein Kinase C (PKC)
family of kinases includes 12 … later), larvae were dissected within 20 minutes into Schneider’s …

Regulation of the SIRT1 signaling pathway in NMDA-induced Excitotoxicity

…, J Wu, J Ma, P Si, L Yin, Y Zhang, LJ Yan, C Zhang - Toxicology Letters, 2020 - Elsevier
… Ca 2+ -dependent PKC makes a major contribution to PKC activation during NMDA
insults. … is PKC-dependent. It is well known that HuR is a substrate for protein kinase C. …

TOR complex 2 is a master regulator of plasma membrane homeostasis

J Thorner - Biochemical Journal, 2022 - portlandpress.com
… (iv) a C-terminal pleckstrin homology (PH) domain specific for … Correspondingly, a
phosphomimetic Avo2 9E allele and an … affects Fpk1 control of yet another protein kinase, Akl1 …

[HTML][HTML] Inhibition of caspase-2 translation by the mRNA binding protein HuR: a novel path of therapy resistance in colon carcinoma cells?

W Eberhardt, U Nasrullah, K Haeussler - Cells, 2019 - mdpi.com
… splicing which gives rise to two proteins with antagonistic … protein kinase C (PKC) triggered
phosphorylation of different … an elegant mechanism how different ITAF activities could be …

Dissecting Transient Protein Interactions Implicated in Cardiovascular Disease: G Protein-Coupled Receptors and Cardiac Myosin-Binding Protein C

AM Touma - 2021 - search.proquest.com
… This study provides an initial model for the impact of G-peptide interactions in … by
cMyBP-C remains unclear due to experimental challenges in dissecting these weak, …

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs

M Pabis, GM Popowicz, R Stehle… - Nucleic acids …, 2019 - academic.oup.com
… increased binding affinity of full-length HuR compared to RRM1,2 (Figure 5E) and the
importance of RRM3 dimerization for function (Figure 6), we propose that dimerization enables

Regulation of TORC2 Function and Localization in Yeast

A Emmerstorfer-Augustin… - Annual Review of Cell and …, 2023 - annualreviews.org
… Like other large protein kinases, folding of a TOR … Furthermore, we found that both a
phosphomimetic Avo2(9E) allele … cerevisiae as a model eukaryotic organism in which to dissect

[HTML][HTML] Regulation of DNA damage response and homologous recombination repair by microRNA in human cells exposed to ionizing radiation

M Szatkowska, R Krupa - Cancers, 2020 - mdpi.com
mutations of 3′UTR microRNA binding sites were more often present in the mitogen-activated
protein kinase … chromatin modification, which allows other DDR protein components to be …