… of upregulated enkephalin/delta opioid receptor signaling vs. … the D2 receptor gene
expression between brain regions). c, d qRT-PCR measurements of the D1 and D2 receptor mRNA …

… Fluorescent in situ hybridization (FISH) method was used to visualize Drd1 and Drd2 mRNA
expression in rat brain tissue. The assay was performed according to RNAscope Multiplex …

… In brain slices, met-enkephalin and inhibition of enkephalin catabolism suppresses intra-…
mRNA expression, which can be reversed by chronic administration of the D2-like receptor …

… result in neuronal loss and loss of D2r expressing neurons in striatum and … expressing
neurons in the striatum also have distinct expression patterns for endogenous opioids; enkephalin …

… experience in vivo and dopamine receptor activation in vitro. … (in Drd1-MSNs) and the
enkephalin precursor Penk (in Drd2-… how gene programs regulate normal and maladaptive brain …

… in region specific receptor mRNA expressions, but the protein expression was the lowest in
… higher level in both the mRNA and protein expressions compared to the control animals (Fig. …

… Endogenous enkephalins mediate reinforcing actions but … dopamine D1 and D2 receptors
in the regulation of proenkephalin mRNA abundance in the striatum and accumbens of the rat …

… role in the NAc, a critical brain region for motivated behavior, is not … Dopamine receptor 2
(D2)-MSNs, which display distinct roles in … mRNA expression changes were measured using …

… receptor-mediated facilitation of dopamine receptor-induced … into the right medial forebrain
bundle followed by vehicle … in gene expression for 5-HT1B, dynorphin, and enkephalin, …

… and gene expression mediated by dopamine in different brain regions, … Here we used
dopamine D2 receptor knockout (D2 −/− ) … Whether the reduced enkephalin response to cocaine …