Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson's disease

C O'Callaghan, FH Hezemans, R Ye, C Rua, PS Jones… - Brain, 2021 - academic.oup.com
… -blind randomized placebo-controlled crossover study, with 40 mg … selective dopamine drugs
122 , 123 and dopamine receptor … of noradrenergic versus dopaminergic modulation of the …

A review of DNA risk alleles to determine epigenetic repair of mRNA expression to prove therapeutic effectiveness in reward deficiency syndrome (RDS): embracing “ …

K Blum, B Steinberg, MC Gondre-Lewis… - Psychology Research …, 2021 - Taylor & Francis
research include dopaminergic and glutaminergic genes. … normalizing dopamine activity in
the brain’s reward system is a … Citation108 We hypothesized that high-resolution fMRI would …

The effect of dopamine D2 receptor blockade on human motor skill learning

EM Taylor, D Curtin, TTJ Chong, MA Bellgrove… - bioRxiv, 2023 - biorxiv.org
study utilized a randomized, double-blind, placebo-controlled… These metabolic changes are
consistent with an fMRI study … of motor learning in conjunction with dopaminergic medication. …

Toward a better understanding of the mechanisms and pathophysiology of anhedonia: are we ready for translation?

DA Pizzagalli - American Journal of Psychiatry, 2022 - Am Psychiatric Assoc
… hubs of the brain reward system have been complemented … vis-à-vis rigorous placebo-controlled
trials. For example, in a … with functional MRI) and negatively associated with dopamine

Dopamine D1R receptor stimulation as a mechanistic pro-cognitive target for schizophrenia

A Abi-Dargham, JA Javitch, M Slifstein… - Schizophrenia …, 2022 - academic.oup.com
… stimulation of cortical dopaminergic receptors, particularly the … DA-depleted rats 54 and
across COMT genotypes in healthy … changes on the prespecified fMRI analysis. The authors …

[PDF][PDF] The Effects of Amphetamine-induced Sensitization and its Relation to Stress, Reward Processing and Decision Making

DM Gomola - 2021 - phaidra.univie.ac.at
… Using a double blind placebo controlled study design, we … affected by the participants
hyperresponsive dopamine system, as a … We used fMRI to collect data on neural activity of healthy …

Dopaminergic mechanisms underlying normal variation in trait anxiety

AS Berry, RL White, DJ Furman… - Journal of …, 2019 - Soc Neuroscience
… individual differences in human dopamine neurochemistry are … of dopamine acts to reduce
anxiety until a tipping point after … Future studies using simultaneous fMRI and PET acquisition …

A randomized controlled experimental medicine study of ghrelin in value-based decision making

M Pietrzak, A Yngve, JP Hamilton… - The Journal of …, 2023 - Am Soc Clin Investig
… significantly reduced after dopamine depletion in the VTA … of our study is its randomized,
placebo-controlled, double-… For first-level, subject-wise analysis of the fMRI data we constructed …

[HTML][HTML] Summary document research on RDS anti-addiction modeling: annotated bibliography

K Blum, D Baron, T McLaughlin… - Journal of addiction …, 2024 - ncbi.nlm.nih.gov
… more research in a larger randomized placebo-controlled study … it induces dopamine
homeostasis regardless of hypo- or hyper-… animal and human placebo-controlled fMRI

Dopaminergic and noradrenergic modulation of stress-induced alterations in brain activation associated with goal-directed behaviour

P van Ruitenbeek, CWEM Quaedflieg… - Journal of …, 2021 - journals.sagepub.com
… not driven by their current reward value, but rather by (rewarding) … MPH’s actions on
extracellular dopamine and noradrenaline … All data except fMRI data were analysed using IBM …