[HTML][HTML] … , and pharmacodynamic cognitive and electrophysiological effects of a dopamine D1 receptor positive allosteric modulator in patients with schizophrenia

A Desai, L Benner, R Wu, L Gertsik, P Maruff… - …, 2021 - nature.com
… ambient dopaminergic tone rather than activating dopamine D 1 receptors independent of
… This multiple ascending-dose study was a double-blind, placebo-controlled trial wherein …

Schizotypal traits are linked to dopamine-induced striato-cortical decoupling: a randomized double-blind placebo-controlled study

J Rössler, L Unterassner, T Wyss, H Haker… - Schizophrenia …, 2019 - academic.oup.com
… We here show that dopaminergic modulation iFC of 6 striatal seeds resulted in a significant
functional decoupling from the right ventral caudate to both occipital fusiform gyri in …

[HTML][HTML] No effect of a dopaminergic modulation fMRI task by amisulpride and L-DOPA on reward anticipation in healthy volunteers

O Grimm, M Nägele, L Küpper-Tetzel, M de Greck… - …, 2021 - Springer
… has been discussed in disorders ranging from schizophrenia … Frankfurt am Main as a
placebo-controlled, double-blind cross-… is modulated by a challenge of the dopamine system using …

The circuitry of dopamine system regulation and its disruption in schizophrenia: insights into treatment and prevention

AA Grace, FV Gomes - Schizophrenia bulletin, 2019 - academic.oup.com
… , a dysfunction in the ability to modulate the DA system in a context-dependent manner is
proposed to underlie the inappropriate interpretation of events that occurs with psychosis. …

Prodopaminergic drugs for treating the negative symptoms of schizophrenia: systematic review and meta-analysis of randomized controlled trials

M Sabe, M Kirschner, S Kaiser - Journal of clinical …, 2019 - journals.lww.com
… as trial registries were searched for placebo-controlled trials. … striatal dopamine release in
response to rewarding stimuli … interest to modulate dopaminergic neurotransmission for the …

Dopamine is a double-edged sword: dopaminergic modulation enhances memory retrieval performance but impairs metacognition

M Clos, N Bunzeck, T Sommer - Neuropsychopharmacology, 2019 - nature.com
… Also, disorders linked with aberrant dopamine function such as schizophrenia or Parkinson’…
retrieval-specific dopaminergic effects. To bridge this gap, we designed a placebo-controlled

Dopamine-induced dysconnectivity between salience network and auditory cortex in subjects with psychotic-like experiences: a randomized double-blind placebo …

J Rössler, W Rössler, E Seifritz… - Schizophrenia …, 2020 - academic.oup.com
modulation and the development of subthreshold psychosis. … dopamine hypothesis of
schizophrenia, where dopaminergic … to the development of schizophrenia spectrum disorders. …

[HTML][HTML] The effects of AUT00206, a novel Kv3. 1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia

SJ Kaar, I Angelescu, MM Nour, TR Marques… - …, 2022 - Springer
… processing, thought to be due to disrupted striatal and dopaminergic function. Consistent …
striatum during reward anticipation in schizophrenia. Dopamine neuron activity is modulated by …

Potent Dopamine D2 Antagonists Block the Reward-Enhancing Effects of Nicotine in Smokers With Schizophrenia

AE Whitton, AI Green, DA Pizzagalli… - Schizophrenia …, 2019 - academic.oup.com
management of schizophrenia, an important question is whether DA D 2 receptor antagonists
modulate … activity within the mesolimbic DA reward system. Nicotine stimulates DA neurons …

Machine learning identifies large-scale reward-related activity modulated by dopaminergic enhancement in major depression

Y Liu, R Admon, MS Mellem, EL Belleau… - Biological Psychiatry …, 2020 - Elsevier
… Using a double-blind, placebo-controlled design, we analyzed … pathway and 2) transient
dopamine enhancement would … disorders such as addiction or schizophrenia [eg, (47,48)]. …