A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes

MA Niewczas, ME Pavkov, J Skupien, A Smiles… - Nature medicine, 2019 - nature.com
… Is the effect of KRIS proteins on renal function decline … a risk factor but a risk indicator of
the disease process leading to … the effect of KRIS proteins on the rate of renal function decline …

… in tubular biomarkers with dietary intervention and metformin in patients with autosomal dominant polycystic kidney disease: a post-hoc analysis of two clinical trials

W Wang, Z You, CN Steele, B Gitomer, M Chonchol… - BMC nephrology, 2024 - Springer
… -consecutive days per week) in non-diabetic adults 18–65 years of age with overweight
or obesity and ADPKD with normal to moderately declined kidney function (eGFR ≥ 30 ml/min/…

Unraveling the role of inflammation in the pathogenesis of diabetic kidney disease

K Matoba, Y Takeda, Y Nagai, D Kawanami… - International journal of …, 2019 - mdpi.com
… of diabetic kidney disease (DKD) continues to rise. DKD is the leading cause of end-stage
renal disease (… mortality due to cardiovascular disease in subjects with diabetes. Evidence is …

Effects of selonsertib in patients with diabetic kidney disease

GM Chertow, PE Pergola, F Chen… - Journal of the …, 2019 - journals.lww.com
… with type 2 diabetes and treatment-refractory moderate-to-advanced diabetic kidney disease,
we randomly assigned 333 adults in a 1:1:1:1 allocation to selonsertib (oral daily doses of 2…

Dietary protein intake, protein energy wasting, and the progression of chronic kidney disease: analysis from the KNOW-CKD study

SW Lee, YS Kim, YH Kim, W Chung, SK Park, KH Choi… - Nutrients, 2019 - mdpi.com
… Gaussian distribution between dietary protein … , diabetes, causes of chronic kidney disease,
urine protein to creatinine ratio, blood urea nitrogen, bilirubin, hemoglobin, body mass index, …

Dietary inflammatory potential in relation to the gut microbiome: results from a cross-sectional study

J Zheng, KL Hoffman, JS Chen, N Shivappa… - … Journal of Nutrition, 2020 - cambridge.org
… of the dietary inflammatory index (DII®) from the University of South Carolina in order to
develop computer and smartphone applications for patient counselling and dietary intervention …

[HTML][HTML] Molecular mechanisms and therapeutic targets for diabetic kidney disease

KR Tuttle, R Agarwal, CE Alpers, GL Bakris… - Kidney international, 2022 - Elsevier
… contribute to disease progression. This review summarizes existing evidence on the molecular
drivers of diabetic kidney disease onset and progression, focusing on inflammatory and …

Innate immunity in diabetic kidney disease

SCW Tang, WH Yiu - Nature Reviews Nephrology, 2020 - nature.com
… that renal inflammation contributes to the pathogenesis and progression of diabetic kidney
disease (DKD) and that anti-inflammatory … Immune cells and resident renal cells that activate …

The role of inflammation in CKD

SP Kadatane, M Satariano, M Massey, K Mongan… - Cells, 2023 - mdpi.com
inflammatory states, the unique effects of inflammation on the kidneys and the relationship
to chronic kidney disease… progression of diabetic kidney disease and heart failure. Recently, …

Canagliflozin reduces inflammation and fibrosis biomarkers: a potential mechanism of action for beneficial effects of SGLT2 inhibitors in diabetic kidney disease

HJL Heerspink, P Perco, S Mulder, J Leierer… - Diabetologia, 2019 - Springer
… of kidney function decline in type 2 diabetes. The aim of this study was to assess the effect of
the … inhibitor canagliflozin on biomarkers for progression of diabetic kidney disease (DKD). …