Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
M Mieresova, K Balazova, J Kubele… - Clinical Case …, 2023 - Wiley Online Library
… /TAZO in critically ill obese patients immediately after the first administered dose. In the context
of … maximization of PIP/TAZO dose at baseline to rapidly saturate increased V d in obese …
of … maximization of PIP/TAZO dose at baseline to rapidly saturate increased V d in obese …
Piperacillin population pharmacokinetics and dosing regimen optimization in critically ill children with normal and augmented renal clearance
A Béranger, S Benaboud, S Urien, F Moulin… - Clinical …, 2019 - Springer
… Piperacillin/tazobactam or piperacillin were prescribed according to local protocol, in
most cases at 75/9.375 or 75 mg.kg −1 , respectively. Antibiotic agents were administered by …
most cases at 75/9.375 or 75 mg.kg −1 , respectively. Antibiotic agents were administered by …
[PDF][PDF] Vancomycin and Linezolid dosing in Obese and Overweight Patients: Is There a Universally Accepted Dosing Protocol to Improve their Efficacy?
… for morbidly obese individuals. The peculiar interactions of several antibiotics are affected by
morbid obesity (… in normal renal functioning morbidly obese patients were developed. It was …
morbid obesity (… in normal renal functioning morbidly obese patients were developed. It was …
The pharmacodynamics of prolonged infusion β-lactams for the treatment of Pseudomonas aeruginosa infections: a systematic review
AK Thabit, ALV Hobbs, OE Guzman, KM Shea - Clinical Therapeutics, 2019 - Elsevier
… intermittent infusion piperacillin/tazobactam or meropenem in critically ill patients with sepsis;
… piperacillin/tazobactam regimens do not consistently achieve goal PTA at an MIC of 16 mg/…
… piperacillin/tazobactam regimens do not consistently achieve goal PTA at an MIC of 16 mg/…
Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli …
… dosing in HFIM, piperacillin/tazobactam and meropenem stock solutions were prepared from
piperacillin/tazobactam (… ) and meropenem (Meropenem, 1000 mg, Fresenius Kabi Pty Ltd, …
piperacillin/tazobactam (… ) and meropenem (Meropenem, 1000 mg, Fresenius Kabi Pty Ltd, …
[HTML][HTML] … dosing for the critically ill: A retrospective analysis of clinical experience with dosing software and therapeutic drug monitoring to optimize antimicrobial dosing
U Chiriac, DC Richter, OR Frey, AC Röhr, S Helbig… - Antibiotics, 2021 - mdpi.com
… were admitted to the intensive care unit (ICU), of which 179 patients received empirical
piperacillin/tazobactam treatment and were included. Moreover, in total, 335 piperacillin …
piperacillin/tazobactam treatment and were included. Moreover, in total, 335 piperacillin …
[HTML][HTML] Population pharmacokinetics of piperacillin in non-critically ill patients with bacteremia caused by Enterobacteriaceae
V Merino-Bohórquez, F Docobo-Pérez… - Antibiotics, 2021 - mdpi.com
… Patients were included only if: the first piperacillin–tazobactam dose was administered in the
… of the therapy was at least 48 h, and the patient was not admitted to the intensive care unit. …
… of the therapy was at least 48 h, and the patient was not admitted to the intensive care unit. …
[HTML][HTML] β-lactam therapeutic drug monitoring in critically ill patients: weighing the challenges and opportunities to assess clinical value
… -based dose optimisation of piperacillin/tazobactam to improve outcome in patients with
sepsis (… on CRRT, and those on ECMO and/or morbid obesity. Prospective studies focusing on …
sepsis (… on CRRT, and those on ECMO and/or morbid obesity. Prospective studies focusing on …
[HTML][HTML] Beta-lactams dosing in critically ill patients with gram-negative bacterial infections: a PK/PD approach
KL Maguigan, MH Al-Shaer, CA Peloquin - Antibiotics, 2021 - mdpi.com
… Piperacillin/tazobactam (TZP) is the only commercially … dosing is recommended in the
package insert, a dosing strategy … in critically ill patients when targeting an MIC of 16 mg/L [20]. …
package insert, a dosing strategy … in critically ill patients when targeting an MIC of 16 mg/L [20]. …
Evaluation of area under the concentration–time curve-guided vancomycin dosing with or without piperacillin-tazobactam on the incidence of acute kidney injury
JD Muklewicz, TD Steuber, JD Edwards - International journal of …, 2021 - Elsevier
… Numerous studies have suggested that the combination of piperacillin-tazobactam (… patients
receiving combination PT and vancomycin developed AKI, compared with 12.9% of patients …
receiving combination PT and vancomycin developed AKI, compared with 12.9% of patients …