Effect of Obesity on Clinical Outcomes of Patients Treated With Cefepime

AR Morrison, JT Loper, KE Barber… - Journal of …, 2021 - journals.sagepub.com
… on clinical outcomes in obese patients treated with cefepime. … dosing strategies on clinical
outcomes of obese patients … single-dose PK data in morbidly obese patients before bariatric …

PiperacillinTazobactam Plus Vancomycin-Associated Acute Kidney Injury in Adults: Can Teicoplanin or Other Antipseudomonal Beta-Lactams Be Remedies?

AT Aslan, M Akova - Healthcare, 2022 - mdpi.com
… In conclusion, future studies should investigate what the optimal threshold for the AUC-guided
VAN dosing strategy should be in patients receiving TZP–VAN combination therapy. …

How Do I Manage the Morbidly Obese Critically Ill Patient?

AA El Solh - Evidence-Based Practice of Critical Care, 2019 - books.google.com
… , 79 intermittent infusion of piperacillin/tazobactam may … of morbidly obese patients with
obese patients, implying that lower loading doses would be an appropriate adjustment for patient

Availability of information for dosing commonly used medications in special ICU populations

C Eastman, BL Erstad - American Journal of Health-System …, 2020 - academic.oup.com
… Examples might include statements such as “Insufficient evidence exists to provide
recommendations for drug dosing in morbidly obese patients” and “Patients receiving ECMO were …

Pharmacokinetics of antibacterial agents in the elderly: the body of evidence

OI Butranova, EA Ushkalova, SK Zyryanov… - Biomedicines, 2023 - mdpi.com
… function, severe hypoalbuminemia, morbid obesity, and other … In general, the dosing of
lipophilic antibiotics in obese patients … A combination of piperacillin tazobactam with vancomycin …

Predictive Factors of Piperacillin Exposure and the Impact on Target Attainment after Continuous Infusion Administration to Critically Ill Patients

J Martínez-Casanova, E Esteve-Pitarch… - Antibiotics, 2023 - mdpi.com
Piperacillin/tazobactam administered by continuous … of piperacillin/tazobactam in critically
ill adult patients with preserved renal function and to determine the empirical optimal dosing

Burn injury and augmented renal clearance: a case for optimized piperacillin-tazobactam dosing

SC Torian, AJ Wiktor, SE Roper… - Journal of Burn Care …, 2023 - academic.oup.com
… Our case contrasts these reports of ARC as our patient had a low TBSA, was morbidly obese,
… on a rational TZP dosing strategy for non-critically ill burn patients with ARC and obesity. …

Towards precision medicine: Therapeutic drug monitoring–guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity

JA Cusumano, KP Klinker, A Huttner… - American Journal of …, 2020 - academic.oup.com
… ill severely obese patients (body mass index [BMI] of >35… patients receiving either conventional
or higher-than-conventional doses of meropenem or piperacillin/tazobactam, with dosing

Antibiotic stewardship and therapeutic drug monitoring of β-lactam antibiotics: Is there a link? An opinion paper

DC Richter, A Heininger, U Chiriac… - Therapeutic Drug …, 2022 - journals.lww.com
… treated with a standard dose of piperacillin/tazobactam (13.5 g/… recommended dose derived
from the noncommercial dosing … the use of TDM in morbidly obese patients, as drug CL may …

Comparison of vancomycin area-under-the-curve dosing versus trough target–based dosing in obese and nonobese patients with methicillin-resistant Staphylococcus …

JR Covvey, O Erickson, D Fiumara… - Annals of …, 2020 - journals.sagepub.com
… With an anticipated change in dosingdosing strategy in patients with and without obesity.
Accordingly, the primary objective of this study was to evaluate vancomycin total daily doses (…