[HTML][HTML] Potential of histone deacetylase inhibitors in the control and regulation of prostate, breast and ovarian cancer
SD Pramanik, A Kumar Halder, U Mukherjee… - Frontiers in …, 2022 - frontiersin.org
… or chemotherapy require newer therapeutic agents. By improving the … cancer cells in 2006,
compared to lung and colon cancer … inhibitors such sirtinol, cambinol, EX527, and suramin. By …
compared to lung and colon cancer … inhibitors such sirtinol, cambinol, EX527, and suramin. By …
Targeting the RNA-binding protein HuR in cancer
… inhibitors of translocation may be less toxic through … gene in human colon cancer cells
under oxidative stress. Mol … Suramin, screened from an approved drug library, inhibits HuR …
under oxidative stress. Mol … Suramin, screened from an approved drug library, inhibits HuR …
New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations
… was able to induce apoptosis in colorectal cancer [28] and to … were found to have a low
toxicity profile based on the in silico … receptor antagonists suramin and theobromine on tumor-…
toxicity profile based on the in silico … receptor antagonists suramin and theobromine on tumor-…
Recent advances in novel drug delivery systems and approaches for management of breast cancer: A comprehensive review
… Silica NPs loaded with dual drugs (PTX and suramin) using … MCF-7 BC cells and human
colorectal cancer cells [155] … Micelles are a therapeutic agent or a carrier to deliver a poorly …
colorectal cancer cells [155] … Micelles are a therapeutic agent or a carrier to deliver a poorly …
Discovery of 5-(or 6)-benzoxazoles and oxazolo [4, 5-b] pyridines as novel candidate antitumor agents targeting hTopo IIα
E Karatas, E Foto, T Ertan-Bolelli, G Yalcin-Ozkat… - Bioorganic …, 2021 - Elsevier
… Discovery of novel anticancer drugs which have low toxicity … and Topo II (aclarubicin and
suramin), stabilize noncovalent DNA … In the present study, it has been observed that the most …
suramin), stabilize noncovalent DNA … In the present study, it has been observed that the most …
Retrospective Review of Chromane Analogues as Anti-protozoal Leads: A Decade's Worth of Evolution
SR Jadhav, B Karan Kumar, RP Joshi… - Current Topics in …, 2023 - ingentaconnect.com
… The parasite selectively takes up suramin via receptor-… Genistein induces apoptosis in HT29
colon cancer cells by reducing … It is also a good therapeutic agent for wound healing [92]. …
colon cancer cells by reducing … It is also a good therapeutic agent for wound healing [92]. …
A third shot at EGFR: new opportunities in cancer therapy
S Guardiola, M Varese, M Sanchez-Navarro… - Trends in …, 2019 - cell.com
… the therapeutic progress achieved with these drugs has been … in cell proliferation, migration,
and differentiation pathways [ … Two classes of anti-EGFR drugs are currently on the market …
and differentiation pathways [ … Two classes of anti-EGFR drugs are currently on the market …
Insight into small-molecule inhibitors targeting extracellular nucleotide pyrophosphatase/phosphodiesterase1 for potential multiple human diseases
B Du, J Ru, Z Zhan, C Lin, Y Liu, W Mao… - European Journal of …, 2024 - Elsevier
… Blue 2 (2) and suramin (3) exhibit low selectivity for ENPP1, as … as cancer therapeutic agents
and vaccine adjuvants [42]. … good inhibition of HT-49 colon cancer cells (IC 50 = 1.4 μM). …
and vaccine adjuvants [42]. … good inhibition of HT-49 colon cancer cells (IC 50 = 1.4 μM). …
Death‐associated protein kinase (DAPK) family modulators: current and future therapeutic outcomes
AK Farag, EJ Roh - Medicinal research reviews, 2019 - Wiley Online Library
… , as well as the LAR activators (suramin derivatives), could be … neuronal cell death after stroke
and brain ischemia provides … human breast cancer, and SW480 colon cancer cell lines.187 …
and brain ischemia provides … human breast cancer, and SW480 colon cancer cell lines.187 …
Employment of enhanced permeability and retention effect (EPR): Nanoparticle-based precision tools for targeting of therapeutic and diagnostic agent in cancer
… to deliver the therapeutic agent at specified cancer tissue site … decrease in death rate in
patients with colon cancer [44]. … like suramin, thrombospondin, thalidomide, endostatin, and …
patients with colon cancer [44]. … like suramin, thrombospondin, thalidomide, endostatin, and …