… The exploitation of peptides as therapeutic agents has … increase in p53 acetylation in
human colon cancer cells [64]. … with the most potent suramin derivative having an IC 50 …

… to find fresh therapeutic agents with low side effects to abide … chemopreventive mediator of
colon cancer, because they do … their higher anti-angiogenic activity than suramin [189,190]. In …

… that disrupt DNA–topo binding (aclarubicin, suramin) [15,16], … and effective anticancer
therapeutic agents, we designed and … (human colon cancer cell line), T47D (human breast cancer …

… On the contrary, agents such as suramin, a potent catalytic … -474), colon cancer (HCT-116),
and (ii) suspension cell lines viz … compounds showed a lower toxicity profile than harmine. All …

… The library was screened at two compound concentrations, … caused by reduced toxicity
due to the use of lower doses in … We provide evidence that GSK-650394, suramin and C646 …

Multifunctional nanoplatforms (MFNPs) have attracted increasing attention because of their
ability to integrate diverse functional diagnostic and therapeutic agents in one system. …

… greater effectiveness and less toxicity [31, 32] to overcome the … the reference standard
inhibitor, suramin (IC50 values against … derivatives showed cytotoxic activity against colon cancer …

… inhibitors, suramin, curcumin and EF24. … breast cancer, hormonal therapy demonstrated
less toxicity and more prolonged palliative effects [19]. EGFR is a well-known oncogene that has …

… of new medicinal and therapeutic agents in cancer treatment … the standard compound,
suramin, carrageenans have been … in the human colon cancer cell line by inducing cell apoptosis …

… 53 had low toxicity toward normal human blood lymphocytes … to inhibition of human colorectal
cancer cell proliferation [67]. … activity better than reference drug suramin with IC 50 values …