Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: study protocol for a randomized double blinded placebo …

J van den Berg, CC Hamel, MP Snijders… - BMC pregnancy and …, 2019 - Springer
Study aim and design The aim of this study is to compare addition of mifepristone to the
standard treatment with misoprostol in terms of complete evacuation of products of conception …

Efficacy and safety of mifepristone in the treatment of male US veterans with posttraumatic stress disorder: a phase 2a randomized clinical trial

JA Golier, X Li, M Bizien, RA Hurley… - JAMA Network …, 2023 - jamanetwork.com
… Thus, this study does not support a phase 3 trial in this … is a steroid with antiglucocorticoid
and antiprogesterone properties … This study was a 12-week, double-blind, placebo-controlled, …

Second-trimester medical abortion with misoprostol preceded by two sequential doses of mifepristone: an observational study

U Shantikumar, R Bagga, J Kalra, V Jain, V Suri… - The Journal of Obstetrics …, 2022 - Springer
three (200 or 400 μg at gestation > 16 weeks or ≤ 16 weeks, respectively, six-hourly) [18,
19]. In the present study, we administered a second dose of mifepristone … -dose mifepristone

Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women

TE Bartlett, I Evans, A Jones, JE Barrett, S Haran… - Genome medicine, 2022 - Springer
… Indeed, this agent has prevented malignant formation in Brca1-deficient mice [29]. …
available number of healthy volunteers treated with antiprogestins (Clinical Trials 1-3, ‘Mifepristone

… progesterone receptor modulators in early-stage breast cancer: a randomized, placebo-controlled phase II window-of-opportunity trial using telapristone acetate

…, B Jovanovic, N Hansen, KP Bethke, PH Gann… - Clinical Cancer …, 2020 - AACR
… In a double-blind presurgical window trial of oral telapristone … of antiprogestin therapies for
breast cancer treatment and … Higher doses of single-agent mifepristone have been tested in …

[HTML][HTML] Clinical utility of mifepristone: apprising the expanding horizons

ZV Karena, H Shah, H Vaghela, K Chauhan, PK Desai… - Cureus, 2022 - ncbi.nlm.nih.gov
… doses of uterotonic agents after mifepristone treatment is the … by randomized, double-blind,
and controlled trials with larger … As an antiprogesterone, mifepristone causes upregulation of …

Mifepristone extends both length and quality of life in a patient with advanced non-small cell lung cancer that has progressed despite chemotherapy and a check-point …

JH Check, D Check, T Poretta - Anticancer Research, 2019 - ar.iiarjournals.org
… (IND), to treat up to 40 patients with stage IIIB or IV non-small … “A phase II study of treatment
with oral mifepristone as salvage … response to single agent mifepristone, which activates the …

The role of mifepristone in the management of meningiomas: A systematic review of literature

R Sharma, K Garg, V Katiyar, V Tandon… - Neurology …, 2019 - journals.lww.com
… Use of mifepristone as a hormonal agent for meningiomas … to achieve an antiprogesterone
effect without significant … One double-blind phase 3 multicentric randomized controlled trial

[HTML][HTML] Comparison of outpatient with inpatient mifepristone usage for cervical ripening: A randomised controlled trial

O Baev, A Karapetian, D Babich, G Sukhikh - European Journal of …, 2023 - Elsevier
… The use of pharmacological agents or mechanical methods to promote cervical ripening …
, this randomised trial is the first to compare the outpatient and inpatient use of mifepristone for …

90 YEARS OF PROGESTERONE: Selective progesterone receptor modulators in gynaecological therapies

HOD Critchley, RR Chodankar - Journal of molecular …, 2020 - jme.bioscientifica.com
… Like mifepristone, UPA was labelled an ‘antiprogestin’ when initially … of phase III clinical trials
utilising UPA for management of … vs placebo in a randomised, double-blind, parallel-group …