… The aim of this study was to compare the efficacy/safety … via the assessment of the change
in transitional dyspnea index (… G/I twice daily at lower dose works better than administering G/I …

… For example, the BLAZE investigators [21] reported in patients with … , our study extends the
previous finding that dual bronchodilation improves patient-reported breathlessness in COPD …

… Patients with COPD obtain greater dyspnea reduction and functional aerobic capacity … Dual
bronchodilation with QVA149 reduces patient-reported dyspnoea in COPD: the BLAZE study …

… at different doses to reduce dyspnea compared with placebo. … Citation22 The following RCT,
named BLAZE study, was … by the clinical COPD questionnaire and the level of dyspnea as …

… For instance, the BLAZE trial studied glycopyrronium (a LAMA) … concluded that dual
bronchodilator therapy significantly reduced … FLIGHT1 and FLIGHT2:Efficacy and safety of …

… efficacy of COPD treatments to reduce exertional dyspnea, … capacity to alleviate patient-reported
dyspnea during activity of … , double-blind cross-over study to compare the effects of dual …

… decreased hyperinflation and improved cardiac function with an improvement of patient-reported
outcomes as indicated by the increases in health status (CAT scores) and dyspnea (TDI …

… suffering from this disease, dyspnea, cough, and sputum … The Global Burden of Disease
Study highlighted that COPD … bronchodilators can reduce hyperinflation, improve dyspnea, …

… COPD, owing to its efficacy in relieving symptoms of dyspnea. … IND/GLY reduced the risk of
acute COPD exacerbations, and … of dual bronchodilation with QVA149 in COPD patients: the …

… from RCTs and observational studies with respect to the risk … a reduced risk of COPD
exacerbation, decreased number of … data, dyspnea by TDI score and COPD exacerbations ECG …