… For quantification, we counted the number of live/dead cells within two sectors per well (at …
of 0.5 mg/kg of U0126 (Cell Signaling Technology) at the beginning of the reperfusion. Control …

… the intervention with CH-I and CBL, the expression of pMEK1/2 in both two groups was …
after stroke. Some evidence has shown that CIRI can activate the MAPK/ERK1/2 signal pathway, …

… 1/2 signaling pathway performs multiple regulatory functions … Thrombolytic therapy is the
most effective treatment for stroke … Akt, VEGF, and MAPK/ERK1/2 signaling pathways, mediates …

… used in the treatment of IS in China and have a wide range of therapeutic effects on IS by
regulating multiple targets and signaling pathways. The keywords “ischemia stroke, traditional …

… After reperfusion, the CBF of two groups almost returned to normal level. The volume of …
Besides, the role of the MAPK/ERK1/2 pathway in ischemic stroke is controversial. Because …

… , the molecular mechanisms of two well-known pro-survival signaling pathways, MAPK/ERK1/2
and PI3K/Akt, that mediate E2 neuroprotection in response to acute ischemic stroke. E2 …

… We examined two features of Cx43 function that may be potential targets for neuroprotection,
specifically, the potential protective benefits provided by GJ coupling and the detrimental …

… Activated reactive astrocytes protect neurons after stroke by … factor, BDNF, and glial cell–derived
neurotrophic factor (Liu … PI3K/Akt signaling pathway exerts multiple cellular functions, …

… stroke pathogenesis. Particularly, BDNF is involved in both MAPK/ERK1/2 and PI3K complex
pathways and … recorded in two days before and one day after establishing the stroke model. …

… Pax6 expression in astrocytes after stroke (Figures 1 and 2), … However, the MAPK/Erk1/2
inhibitor (U0126) causes some … MAPK/Erk pathway is able to play multiple roles by regulating …