Juvenile pilocytic astrocytomas: A search for prognostic markers
N Osman - 2022 - open.uct.ac.za
… The cerebellar pilocytic astrocytomas classically show a cyst … described is a duplication at
chromosome 7q34 whereby the … as specific in confirming a diagnosis of pilocytic astrocytoma …
chromosome 7q34 whereby the … as specific in confirming a diagnosis of pilocytic astrocytoma …
Circumscribed astrocytic gliomas
… of cysts, a hallmark present in more than 80 per cent of cerebellar … More specific is the
presence of αB-crystallin.… copy number gain of the BRAF gene on 7q34 in a large proportion of …
presence of αB-crystallin.… copy number gain of the BRAF gene on 7q34 in a large proportion of …
ATRX protein loss and deregulation of PI3K/AKT pathway is frequent in pilocytic astrocytoma with anaplastic features
A Olar, D Tran, VP Mehta, A Reinhardt… - Clinical …, 2019 - search.proquest.com
… The pyrosequencing primer used for amplifying BRAF at 7q34 … 3) showed BRAF fusion/duplication
by pyrosequencing; 1 of … astrocytomas and a hallmark of cerebellar and optic pathway …
by pyrosequencing; 1 of … astrocytomas and a hallmark of cerebellar and optic pathway …
The involvement of the MAPK pathway in pilocytic astrocytomas
… of cortical neurogenesis, and midbrain and cerebellum development. Alterations in this
pathway … This duplication at 7q34 is practically specific for pilocytic astrocytomas as it is rare or …
pathway … This duplication at 7q34 is practically specific for pilocytic astrocytomas as it is rare or …
Genetic and histopathological associations with outcome in pediatric pilocytic astrocytoma
SJ Cler, A Skidmore, AT Yahanda, K Mackey… - Journal of …, 2022 - thejns.org
… astrocytomas (PAs), the most common CNS tumor in children, 1 are most commonly located
in the cerebellum … Cerebellar PAs are associated with a higher rate of gross-total resection (…
in the cerebellum … Cerebellar PAs are associated with a higher rate of gross-total resection (…
Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis
N Manoharan, P Ajuyah, A Senapati, M Wong… - Acta Neuropathologica …, 2021 - Springer
… A radiological hallmark of this disease is widespread … , Sylvian fissures, brainstem and
cerebellar folia. Discrete parenchymal … loss and 7q34 gain associated with both classes, but more …
cerebellar folia. Discrete parenchymal … loss and 7q34 gain associated with both classes, but more …
Adult pilocytic astrocytoma in the molecular era: a comprehensive review
TA Gregory, LB Chumbley, JW Henson… - CNS oncology, 2021 - Taylor & Francis
… This is distinct from pediatric PA where cerebellar and cerebral/lobar … duplication of
chromosome 7q34 was reported as a frequent chromosomal abnormality in PA. The 7q34 …
chromosome 7q34 was reported as a frequent chromosomal abnormality in PA. The 7q34 …
[HTML][HTML] Pathological perspectives in pilocytic astrocytomas: Extent of resection as the sole critical factor for recurrence-free survival, and the challenge of evaluating …
… PA is most commonly located in the posterior fossa, specifically in cerebellar hemispheres.
… The most common genetic alteration is the BRAF internal tandem duplication resulting with a …
… The most common genetic alteration is the BRAF internal tandem duplication resulting with a …
Targeted molecular characterization of adult midline and circumscribed gliomas for the identification of new potential targets for personalized therapy
E Trisolini - 2020 - iris.uniupo.it
… The biphasic pattern is best seen in cerebellar tumours. … an approximately 2 Mb duplication
of 7q34, encompassing the … with a histological hallmark of a specific glioneuronal element …
of 7q34, encompassing the … with a histological hallmark of a specific glioneuronal element …
Copy number assessment in the genomic analysis of CNS neoplasia: an evidence-based review from the cancer genomics consortium (CGC) working group on …
SG Neill, J Hauenstein, MM Li, YJ Liu, M Luo, DF Saxe… - Cancer Genetics, 2020 - Elsevier
… for these diagnostically relevant hallmark genomic changes. … in the cerebellum and represent
the most common glioma … majority show a tandem duplication at 7q34 involving gain of …
the most common glioma … majority show a tandem duplication at 7q34 involving gain of …