[HTML][HTML] Consensus recommendation for mouse models of ocular hypertension to study aqueous humor outflow and its mechanisms

CM McDowell, K Kizhatil, MH Elliott… - … & visual science, 2022 - iovs.arvojournals.org
outflow resistance and thus intraocular pressure. In addition, … It is well known that anesthesia
affects IOP, and care should … as either having no effect on IOP or reducing IOP in a time-…

Changes in Intraocular Pressure following Narcosis With Medetomidine, Midazolam, and Fentanyl in Association With Initial Intraocular Pressure in Mice

M Binter, P Lüdtke, F Langer, T Schigiel… - Current Eye …, 2022 - Taylor & Francis
… of decreased intraocular pressure (IOP) under general anesthesia with … We described the
decreasing effect of anesthesia with … Furthermore, we could show that this decline is time-…

Effects of general anesthesia on intraocular pressure in rabbits

JJ Chae, MR Prausnitz… - Journal of the American …, 2021 - ingentaconnect.com
… rapid recovery from anesthesia and near real-time control of the … that appears to be specific
to this combination of anestheticEffect of general anesthetics on IOP in elevated IOP mouse

[HTML][HTML] Effect of anesthesia on intraocular pressure measured with continuous wireless telemetry in nonhuman primates

JV Jasien, CA Girkin, JC Downs - … ophthalmology & visual …, 2019 - tvst.arvojournals.org
time-point (snapshot) IOP measurements, but comparisons were … effect of the different
types of anesthesia on IOP in NHPs, which is especially important for glaucoma researchers that

Increased episcleral venous pressure in a mouse model of circumlimbal suture induced ocular hypertension

VHY Wong, D Zhao, BV Bui, CJ Millar… - Experimental Eye …, 2021 - Elsevier
… or episcleral vein outflow routes to elevate eye pressure. For … Two days later, under isoflurane
anesthesia, the suture was cut … 2 days) without any long term IOP elevation exhibited the …

Single transient intraocular pressure elevations cause prolonged retinal ganglion cell dysfunction and retinal capillary abnormalities in mice

X Tao, RR Sigireddi, PD Westenskow, R Channa… - Experimental eye …, 2020 - Elsevier
… IOP was measured under isoflurane anesthesia with a … marked delay in center STA peak
time at all time points. The … , but not all RGC properties were equally affected in this study…

Effects of acute stress, general anesthetics, tonometry, and temperature on intraocular pressure in rats

CM Nicou, A Pillai, CL Passaglia - Experimental eye research, 2021 - Elsevier
… The rise time was not examined but the duration lasted over an hour after immobilization.
An … is less consensus about the effect of general anesthetics on IOP, and the consensus that

The ocular pulse decreases aqueous humor outflow resistance by stimulating nitric oxide production

M Madekurozwa, WD Stamer… - … of Physiology-Cell …, 2021 - journals.physiology.org
… the time-varying intraocular pressure with a pressure … studies, we confirmed that when the
eye pressure was set to 0 … rate into a cadaveric mouse eye was not significantly different from …

A reversible silicon oil-induced ocular hypertension model in mice

J Zhang, F Fang, L Li, H Huang, HC Webber… - JoVE (Journal of …, 2019 - jove.com
… chamber to return elevated intraocular pressure to normal. … can be used to test the effect of
lowering IOP on glaucomatous … the length of the tunnel, some other critical points are worth …

Optogenetic modulation of intraocular pressure in a glucocorticoid-induced ocular hypertension mouse model

TJ Kowal, PP Prosseda, K Ning, B Wang… - … Vision Science & …, 2021 - tvst.arvojournals.org
… Each eye received 1 drop of proparacaine topical anesthesia, … At this time, one eye was
optogenetically activated using a … side effects, including the development of elevated IOP, that