Overexpression of microRNA-29b inhibits epithelial-mesenchymal transition and angiogenesis of colorectal cancer through the ETV4/ERK/EGFR axis

Y Leng, Z Chen, H Ding, X Zhao, L Qin, Y Pan - Cancer Cell International, 2021 - Springer
… significant regression, but more abundant residual tumors than single … In conclusion, the
results showed that the transcription factor … Additionally, ETV4 can act as an oncogenic protein to …

Interplay among SNAIL transcription factor, microRNAs, long non-coding RNAs, and circular RNAs in the regulation of tumor growth and metastasis

K Skrzypek, M Majka - Cancers, 2020 - mdpi.com
… 2 (FGF2), epidermal growth factor (EGF), Harvey rat sarcoma … Some miRNAs can behave
as oncogenes favoring … activates the transcription of miR-21 to produce exosomes abundant in …

[HTML][HTML] The interaction between ETS transcription factor family members and microRNAs: a novel approach to cancer therapy

L Du, Y Liu, C Li, J Deng, Y Sang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
MiRNAs can target the 3’UTR of ETS factors and inhibit the … the parental gene and increases
parental gene expression. … suppressors, but some oncogenic miRNAs are also upregulated …

[HTML][HTML] MicroRNAs involved in the EGFR pathway in glioblastoma

B Xu, J Mei, W Ji, Z Huo, Z Bian, J Jiao, X Li… - Biomedicine & …, 2021 - Elsevier
miRNAs may function as tumor suppressors or oncogenes [3]. … the expression of the epidermal
growth factor receptor (EGFR… C-myc, the common downstream transcription factor of TGF/β…

Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer

HT Wu, HT Zhong, GW Li, JX Shen, QQ Ye… - Journal of translational …, 2020 - Springer
… -β, β-catenin, miRNA and other factors. Here, we summarize … antibody against human
epidermal growth factor receptor 2 (… be inhibited by nuclear enriched abundant transcript 1 …

[HTML][HTML] Inside the stemness engine: Mechanistic links between deregulated transcription factors and stemness in cancer

EH Ervin, R French, CH Chang, S Pauklin - Seminars in cancer biology, 2022 - Elsevier
transcription factors and stemness in cancer. In particular, we describe the role of master
transcription factors (… and RUNX), signalling-regulated transcription factors (SMAD, β-catenin, …

Regulatory mechanism of MicroRNA expression in cancer

Z Ali Syeda, SSS Langden, C Munkhzul, M Lee… - International journal of …, 2020 - mdpi.com
… Dysfunction of miRNAs disturbs expression of oncogenic or tumor-… methylation of miRNA
genomic loci and the transcription factor-… Epidermal growth factor receptor (EGFR) signaling is …

EGFR in cancer: Signaling mechanisms, drugs, and acquired resistance

ML Uribe, I Marrocco, Y Yarden - Cancers, 2021 - mdpi.com
… in brain tumors, frequent oncogenic point mutants of EGFR have … BAD and FOXO family
transcription factors. AKT can also … Unlike ID-miRs, a set of 22 microRNAs were induced by EGF

The impact of microRNAs in breast cancer angiogenesis and progression

EN Kontomanolis, Z Fasoulakis, V Papamanolis… - …, 2019 - ingentaconnect.com
… along with the contribution of the EGF, TNF-a and EGF cytokines. … is a transcription factor
that was found to decrease the above … oncogene translation and cancer development [54-57]. …

Are transcription factors plausible oncotargets for triple negative breast cancers?

M Marqués, MA Sorolla, I Urdanibia, E Parisi, I Hidalgo… - Cancers, 2022 - mdpi.com
… mechanisms due to oncogenic transcription factors (TFs) … as epidermal growth factor
receptor (EGFR)/FOXC1/Nuclear … induce the transcription of miRNA strands 5p and 3p. Both …