[HTML][HTML] Eph receptors in cancer
… Mutations in Eph receptors also occur in various tumour types and are suspected to … of Ephs
in various cancers. In this review, we discuss the variations in Eph expression and functions …
in various cancers. In this review, we discuss the variations in Eph expression and functions …
The role of Eph receptors in cancer and how to target them: novel approaches in cancer treatment
OJ Buckens, B El Hassouni, E Giovannetti… - Expert opinion on …, 2020 - Taylor & Francis
… In various cancers, the expression of Eph receptors and their … Remarkably, Eph receptors
can either have a tumor … of Eph receptors could become a useful tool for cancer treatment …
can either have a tumor … of Eph receptors could become a useful tool for cancer treatment …
Eph receptors and ephrins in cancer progression
EB Pasquale - Nature Reviews Cancer, 2024 - nature.com
… Eph system in tumour angiogenesis is well established, but recent findings also demonstrate
roles in immune cells, cancer-… targeting of Eph receptors–ephrins in cancer and conclude …
roles in immune cells, cancer-… targeting of Eph receptors–ephrins in cancer and conclude …
[HTML][HTML] The role of the Eph receptor family in tumorigenesis
M Anderton, E van der Meulen, MJ Blumenthal… - Cancers, 2021 - mdpi.com
… cancer-targeting strategies can be developed. This review comprehensively summarises
the … knowledge of Eph receptor implications in oncogenesis in a tissue- and receptor-specific …
the … knowledge of Eph receptor implications in oncogenesis in a tissue- and receptor-specific …
[HTML][HTML] Antibody targeting of Eph receptors in cancer
… While the complex nature of Eph-ephrin actions in development and cancer have been …
of antibodies targeting the Eph-ephrin system in the context of cancer, highlighting the promise …
of antibodies targeting the Eph-ephrin system in the context of cancer, highlighting the promise …
[HTML][HTML] Eph receptor signalling: from catalytic to non-catalytic functions
… interactions between Eph receptors intracellular … of Eph receptors with relevance to cancer,
which are further substantiated by exploring the role of the two pseudokinase Eph receptors, …
which are further substantiated by exploring the role of the two pseudokinase Eph receptors, …
Eph receptors in the immunosuppressive tumor microenvironment
The tumor microenvironment (TME) promotes tumor development via complex intercellular
signaling, aiding tumor growth and suppressing immunity. Eph receptors (Eph) and their …
signaling, aiding tumor growth and suppressing immunity. Eph receptors (Eph) and their …
Eph receptors as cancer targets for antibody-based therapy
FHF Tang, D Davis, W Arap, R Pasqualini… - Advances in cancer …, 2020 - Elsevier
… , Eph receptors are the largest group. Together with their corresponding ephrin ligands, Eph
receptors … Deregulation of Eph signaling pathways is linked to cancer and other proliferative …
receptors … Deregulation of Eph signaling pathways is linked to cancer and other proliferative …
Signals transduced by Eph receptors and ephrin ligands converge on MAP kinase and AKT pathways in human cancers
A Lau, N Le, C Nguyen, RP Kandpal - Cellular Signalling, 2023 - Elsevier
… EphA2 and EphB4 are two of the most extensively studied Eph receptors in breast cancer
cells. EphA2 is overexpressed in 60-80% of breast cancers as compared to normal human …
cells. EphA2 is overexpressed in 60-80% of breast cancers as compared to normal human …
[HTML][HTML] Overexpressed gene signature of EPH receptor A/B family in cancer patients-comprehensive analyses from the public high-throughput database
… expressions of EPH receptors in different cancer subtypes, … Expression ratios of cancer
versus normal tissues are … of most EPH receptors genes increased in diverse types of cancers. …
versus normal tissues are … of most EPH receptors genes increased in diverse types of cancers. …
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