The liver sinusoid in chronic liver disease: NAFLD and NASH

WWJ Kwanten, SM Francque - Sinusoidal Cells in Liver Diseases, 2024 - Elsevier
… In conclusion, structural and functional alterations related to IHVR and sinusoidal liver blood
… importance of ET-1 signaling in early NAFLD with lowering the NAFLD-induced increase in …

Labile heme impairs hepatic microcirculation and promotes hepatic injury

FA Englert, RA Seidel, K Galler, Z Gouveia… - Archives of biochemistry …, 2019 - Elsevier
… As the liversinusoidal microcirculation and hepatocellular integrity. We here provide
experimental evidence that heme increases portal pressure via a mechanism that involves hepatic

[HTML][HTML] Portal hypertension in patients with nonalcoholic fatty liver disease: Current knowledge and challenges

A Madir, I Grgurevic, EA Tsochatzis… - World Journal of …, 2024 - ncbi.nlm.nih.gov
… and damage to liver microcirculation. The severity of PH tends to be underestimated by …
around the sinusoid. IHVR is also elevated by extrasinusoidal compression caused by swollen …

Maternal microvascular dysfunction during preeclamptic pregnancy

AE Stanhewicz, VR Nuckols, GL Pierce - Clinical Science, 2021 - portlandpress.com
microcirculatory resistance, sinusoidal obstruction and … in NO bioavailability within the
hepatic microcirculation. The … is sensitive to the vasoconstrictor activity of ET-1 [56–58] and …