Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease

, … and the Dominantly Inherited Alzheimer Network - Brain, 2021 - academic.oup.com
… For the evaluation of late-onset Alzheimer’s disease, we … In DIAN, we first tested whether
higher EYO was associated … control mechanisms such as hub connectivity in cognitive control …

10,000 social brains: sex differentiation in human brain anatomy

H Kiesow, RIM Dunbar, JW Kable, T Kalenscher… - Science …, 2020 - science.org
… In summary, earlier findings suggest that sex idiosyncrasies in the neurocognitive … network
of our social brain atlas, a series of volume effects was observed in these parts of the human

Default-mode network streams for coupling to language and control systems

EM Gordon, TO Laumann, S Marek… - Proceedings of the …, 2020 - National Acad Sciences
… metrics to first determine whether examining brain subnetwork … the network substructure of
individual human brains using … the brain’s network structure serving as sets of connector hubs

Diagnostic power of resting‐state fMRI for detection of network connectivity in Alzheimer's disease and mild cognitive impairment: A systematic review

B Ibrahim, S Suppiah, N Ibrahim… - Human brain …, 2021 - Wiley Online Library
… reflects the diversity of a region's cross-network FCs. A “hub” is defined as a node that has a
… We first provide some basic definitions with respect to the classifier methods that are utilized …

[HTML][HTML] Regional Aβ-tau interactions promote onset and acceleration of Alzheimer's disease tau spreading

WJ Lee, JA Brown, HR Kim, R La Joie, H Cho, CH Lyoo… - Neuron, 2022 - cell.com
… imaging and network connectivity analyses in living humans, … First, we show that the
lateral entorhinal cortex, an early site … hubs. Specifically, we searched a library of normative …

Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

AP Wingo, W Fan, DM Duong, ES Gerasimov… - Nature …, 2020 - nature.com
… We performed PWAS and protein co-expression networkearly contribution to AD
development 3,4 , surrogate brain … We defined hub proteins as those in the top 20% with regard …

Multicellular communities are perturbed in the aging human brain and Alzheimer's disease

A Cain, M Taga, C McCabe, GS Green… - Nature …, 2023 - nature.com
… .1, while a susceptibility gene for late-onset AD—clusterin (CLU) 24 … To model those, we built
a network of cell subsets, with … We first identified all expressed LRPs (P < 0.05, permutation …

[HTML][HTML] Neuronal excitation/inhibition imbalance: core element of a translational perspective on Alzheimer pathophysiology

F Maestú, W de Haan, MA Busche, J DeFelipe - Ageing Research Reviews, 2021 - Elsevier
… at the macro-level in human studies of early AD, that (indirectly) … high-level modeling of human
brain network dynamics allows … The hubs of the default mode network are brain areas with …

Mapping adolescent reward anticipation, receipt, and prediction error during the monetary incentive delay task

Z Cao, M Bennett, C Orr, I Icke… - Human brain …, 2019 - Wiley Online Library
… and connectivity patterns between males and females, and between early and late pubertal
… Finally, we correlated sensation seeking scores with brain activation and connectivity during …

[HTML][HTML] Electrophysiological maturation of cerebral organoids correlates with dynamic morphological and cellular development

SR Fair, D Julian, AM Hartlaub, ST Pusuluri, G Malik… - Stem cell reports, 2020 - cell.com
… the electrophysiological and neural network features of COs; … , our current knowledge of
human brain development is largely … We first subjected COs to scRNA-seq at late developmental …