Evaluation of analgesic and anti-inflammatory activity of purine-2, 6-dione-based TRPA1 antagonists with PDE4/7 inhibitory activity
M Zygmunt, M Ślusarczyk, A Jankowska… - Pharmacological …, 2022 - Springer
… cold plate tests, and in the carrageenan-induced edema model… most potent antinociceptive
activity in the formalin test was … in the inflammatory processes is a delayed effect that occurs …
activity in the formalin test was … in the inflammatory processes is a delayed effect that occurs …
Antinociceptive effect of the hydroethanolic leaf extract of Calotropis procera (Ait) R. Br.(Apocynaceae): Possible involvement of glutamatergic, cytokines, opioidergic …
… effects exhibited by CPE (100 mg/kg) in the formalin test was … to that of non-selective NSAIDs,
with a reduced risk of certain … effect, as demonstrated by the protracted delay in response …
with a reduced risk of certain … effect, as demonstrated by the protracted delay in response …
[HTML][HTML] Specialized pro-resolving lipid mediators: A new class of non-immunosuppressive and non-opioid analgesic drugs
V Fattori, TH Zaninelli, FS Rasquel-Oliveira… - Pharmacological …, 2020 - Elsevier
… for example, the use of morphine is related to a delay in NF-κB-… , and LXB 4 reduce edema
and thermal hyperalgesia induced … reduces the second phase of formalin-induced overt pain-…
and thermal hyperalgesia induced … reduces the second phase of formalin-induced overt pain-…
[HTML][HTML] Chemical composition, antioxidant, anti-inflammatory and antinociceptive activities of the ethanol extract of ripe fruits of Solanum lycocarpum St. Hil …
MG Morais, AA Saldanha, JPC Rodrigues… - Journal of …, 2020 - Elsevier
… Pain involves mechanisms related to the response of the … effect observed in the first phase
of the formalin test. … potential, provoking the reduction of ear edema induced by chroton oil and …
of the formalin test. … potential, provoking the reduction of ear edema induced by chroton oil and …
Chemical characterization, anti-nociceptive and anti-inflammatory activities of Plukenetia conophora seed oil in experimental rodent models
AM Ajayi, CB Ola, MB Ezeagu, PA Adeleke… - Journal of …, 2023 - Elsevier
… No noticeable sign of acute toxicity or delayed toxicity was … Naloxone did not significantly
reverse the antinociceptive … The oedema reduction is comparable to those obtained from the …
reverse the antinociceptive … The oedema reduction is comparable to those obtained from the …
[PDF][PDF] Antinociceptive and antiinflammatory studies on Tradescantia zebrina
… compromise the immune system, cause infections, and delay the diagnosis and treatment of
… of the formalin test.Based on our results from the carrageenan-induced paw edema test, the …
… of the formalin test.Based on our results from the carrageenan-induced paw edema test, the …
[HTML][HTML] Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel
… reduction of induced twitches (P < 0.005) in mice and edema … subcutaneous injection (0.1
ml) of formaldehyde (4%) at the left … delayed T max (4 h) in the transdermal therapy of F4 may …
ml) of formaldehyde (4%) at the left … delayed T max (4 h) in the transdermal therapy of F4 may …
Discovery of RC-752, a Novel Sigma-1 receptor antagonist with antinociceptive activity: a promising tool for fighting neuropathic pain
… the swim bladder was not well inflated, and oedema was evident. … related to a potentially
recoverable developmental delay or … The formalin test was chosen as a tonic pain model for the …
recoverable developmental delay or … The formalin test was chosen as a tonic pain model for the …
[PDF][PDF] Anti-inflammatory effects of propoxazepam on different models of inflammation
NY Golovenko, TA Kabanova… - … of Medicine and …, 2019 - ojs.tdmu.edu.ua
… proved to reduce the volume of acute inflam matory paw edema in … However, formalin test is
sensitive to non-steroidal … antinociceptive effect while at a higher dose (10 mg/kg) had nearly …
sensitive to non-steroidal … antinociceptive effect while at a higher dose (10 mg/kg) had nearly …
Anti-inflammatory and antinociceptive activities of a phenylpropanoid-enriched fraction of Duguetia furfuracea
… Moreover, the in vivo antinociceptive effect was assayed using the formalin test and …
Treatment with the EFDf also resulted in significant paw oedema reduction in the … Full size image …
Treatment with the EFDf also resulted in significant paw oedema reduction in the … Full size image …