Ulinastatin exhibits antinociception in rat models of acute somatic and visceral pain through inhibiting the local and central inflammation
MX Zhan, L Tang, YF Lu, HH Wu, ZB Guo… - Journal of Pain …, 2021 - Taylor & Francis
… of ulinastatin was also able to delay the occurrence of acetic … studies, the magnitude of paw
edema was calculated as the … also persistently inhibit formalin-induced paw edema and ulcer …
edema was calculated as the … also persistently inhibit formalin-induced paw edema and ulcer …
[HTML][HTML] Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity, and acid-sensing ion channel 3–dependent …
A Jurczak, L Delay, J Barbier, N Simon, E Krock… - Pain, 2022 - journals.lww.com
… accompanied by bone erosion in the absence of joint edema … (RANKL) antibodies, are
antinociceptive in animal models of … The scanning was made at a 10-µm voxel size with an X-ray …
antinociceptive in animal models of … The scanning was made at a 10-µm voxel size with an X-ray …
Anti-inflammatory and antinociceptive effects, and safety toxicological profile of a new paracetamol analog, LQFM291
LC Turones, LS Machado, BG Vaz… - …, 2023 - Springer
… , paracetamol showed a delayed antinociceptive and anti-… to relief pain and inflammatory
signs in patients with chronic … reduced the carrageenan-induced paw edema from the first …
signs in patients with chronic … reduced the carrageenan-induced paw edema from the first …
[HTML][HTML] Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel
… reduction of induced twitches (P < 0.005) in mice and edema (… resulting in particle size
enlargement, reduction of EE% and … and delayed T max (4 h) in the transdermal therapy of F4 may …
enlargement, reduction of EE% and … and delayed T max (4 h) in the transdermal therapy of F4 may …
[HTML][HTML] … of Cajanus cajan (L) Millsp. produced antinociceptive and anti-inflammatory actions through inhibition of inflammatory mediators and activation of opioidergic …
TG Olubodun-Obadun, IO Ishola, CA Osumuo… - Phytomedicine Plus, 2023 - Elsevier
… the early and late phases of formalin-induced inflammatory pain… , we did not observe any
sign of toxic behaviour nor delayed … In this study, the oedema formation was maximal at 5 h after …
sign of toxic behaviour nor delayed … In this study, the oedema formation was maximal at 5 h after …
[HTML][HTML] Specialized pro-resolving lipid mediators: A new class of non-immunosuppressive and non-opioid analgesic drugs
V Fattori, TH Zaninelli, FS Rasquel-Oliveira… - Pharmacological …, 2020 - Elsevier
… , for example, the use of morphine is related to a delay in NF-κB-… 4 , and LXB 4 reduce edema
and thermal hyperalgesia induced … reduces patient assessed joint pain intensity, morning …
and thermal hyperalgesia induced … reduces patient assessed joint pain intensity, morning …
Antinociceptive and anti-inflammatory effect of Naringenin in different nociceptive and inflammatory mice models
N Xue, X Wu, L Wu, L Li, F Wang - Life sciences, 2019 - Elsevier
… The analgesics morphine delays the tail withdrawal of mice … by mice on first phase to smoothen
the neurogenic pain (0–5 … The size of carrageenan induced paw edema was measured …
the neurogenic pain (0–5 … The size of carrageenan induced paw edema was measured …
Antinociceptive effects of hyaluronic acid on monoiodoacetate-induced ankle osteoarthritis in rats
S Jimbo, Y Terashima, A Teramoto… - Journal of Pain …, 2019 - Taylor & Francis
… OA has the distinct disadvantage of prolonged delay and is … effect size was observed, and
the use of multiple doses is likely … In the present study, no improvement in ankle swelling was …
the use of multiple doses is likely … In the present study, no improvement in ankle swelling was …
[HTML][HTML] Antinociceptive and antiinflammatory activities of crude leave extract and solvent fractions of Commelina latifolia Hochst. ex CBClarke (Commelinaceae) …
… edema model was used to test the extracts’ ability to reduce … 0.84) was considered when
calculating the sample size for each … The MO10 group had a significantly delayed pain reaction …
calculating the sample size for each … The MO10 group had a significantly delayed pain reaction …
Ultramicronized N-palmitoylethanolamine associated with analgesics: Effects against persistent pain
S Nobili, L Micheli, E Lucarini, A Toti… - Pharmacology & …, 2024 - Elsevier
… Reducing particle size is a useful method to increase surface area, … first-line treatment for
mild-to-moderate pain, although it is sometimes indicated in combination with opioids to reduce …
mild-to-moderate pain, although it is sometimes indicated in combination with opioids to reduce …