High-altitude cerebral edema: its own entity or end-stage acute mountain sickness?

REF Turner, H Gatterer, M Falla… - Journal of Applied …, 2021 - journals.physiology.org
… logical to assume that brain edema should be present early during exposure and in … edema)
within cerebral white matter with acute hypoxic exposure and more so in persons with acute

[HTML][HTML] Impact of perinatal hypoxia on the developing brain

M Piešová, M Mojmír - Physiological research, 2020 - ncbi.nlm.nih.gov
… stages: the first stage of early cellular death and brain injury is … hypoxia acutely affected
neuronal migration in the brain of the … any acute inflammation or cell death right after the hypoxia, …

Acute and evolving MRI of high-altitude cerebral edema: microbleeds, edema, and pathophysiology

PH Hackett, PR Yarnell, DA Weiland… - American Journal of …, 2019 - Am Soc Neuroradiology
First, we found that extensive WM microbleeds were already present on the initial MR … of
red cells, triggered by uneven hypoxic pulmonary vasoconstriction. Retinal hemorrhages are …

Mild hypoxia triggers transient blood–brain barrier disruption: a fundamental protective role for microglia

SK Halder, R Milner - Acta Neuropathologica Communications, 2020 - Springer
hypoxic spinal cord [17]. In light of the importance of an intact BBB in the maintenance of
cerebral health, and the occurrence of hypoxia … In the first instance, we focused our analysis in …

The critical role of spreading depolarizations in early brain injury: consensus and contention

RD Andrew, JA Hartings, C Ayata, KC Brennan… - Neurocritical care, 2022 - Springer
… mechanisms leading to electrical failure, neuronal swelling, and blood vessel constriction in
newly … Also effective is severe hypoxia in an interface slice chamber [62, 63]. Similarly, SD is …

Haemodynamic instability and brain injury in neonates exposed to hypoxia–ischaemia

S Badurdeen, C Roberts, D Blank, S Miller… - Brain sciences, 2019 - mdpi.com
… We summarise evidence showing that early umbilical cord clamping contributes to
haemodynamic instability and brain injury, and we outline possible brain-protective resuscitation …

Hypoxic‐ischemic‐related cerebrovascular changes and potential therapeutic strategies in the neonatal brain

C Disdier, BS Stonestreet - Journal of neuroscience research, 2020 - Wiley Online Library
… Disruption of the blood–brain barrier (BBB) observed in the early hours after an HI-related
event is … , predispose to cerebral edema, and promote entry of neurotoxic substances into the …

[HTML][HTML] Hypoxia and brain aging: Neurodegeneration or neuroprotection?

J Burtscher, RT Mallet, M Burtscher, GP Millet - Ageing research reviews, 2021 - Elsevier
… To this end we first provide a mechanistic overview on hypoxia adaptations, followed by a …
effects of hypoxia on aging with a focus on the brain. Reports of direct comparisons of hypoxia

Early pro-inflammatory microglia activation after inflammation-sensitized hypoxic-ischemic brain injury in neonatal rats

M Serdar, K Kempe, M Rizazad, J Herz… - Frontiers in cellular …, 2019 - frontiersin.org
… after inflammation-sensitized HI brain injury. We performed this study investigating early
our newborn animal model of inflammation-sensitized HI brain injury, better understanding …

Hypoxic-inflammatory responses under acute hypoxia: in vitro experiments and prospective observational expedition trial

T Kammerer, V Faihs, N Hulde, M Stangl… - International journal of …, 2020 - mdpi.com
… to hypobaric hypoxia-induced AMS and high altitude cerebral edema (… is induced by hypoxia
and by inflammation and exercise … trial, we first analyzed in vitro the effects of hypoxic and …