The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
… to the new threat posed by emerging SARS-CoV-2 variants. Given the wide public interest
in … In vitro neutralization experiments of SARS-CoV-2 variants are usually reported as a fold …

Early detection and surveillance of SARS-CoV-2 genomic variants in wastewater using COJAC

K Jahn, D Dreifuss, I Topolsky, A Kull… - Nature …, 2022 - nature.com
… of SARS-CoV-2 variants of concern and variants of interest … of COJAC to detect emerging
variants early for the Delta variant by … experiments (insufficient coverage/no SARS-CoV-2 RNA …

CRISPR-Cas12a-based detection for the major SARS-CoV-2 variants of concern

Y Liang, H Lin, L Zou, J Zhao, B Li, H Wang… - Microbiology …, 2021 - Am Soc Microbiol
SARS-CoV-2 genetic lineages as specific variants of interest (… Until now, all the experiments
were done using SARS-CoV-2 … S lineage SARS-CoV-2 that emerged in the early stages of …

[HTML][HTML] Rapid screening for SARS-CoV-2 variants of concern in clinical and environmental samples using nested RT-PCR assays targeting key mutations of the spike …

G La Rosa, P Mancini, GB Ferraro, C Veneri… - Water research, 2021 - Elsevier
… The emergence of the new SARS-CoV-2 variant has … samples for screening and early
detection of SARS-CoV-2 variants. … associated with known VOCs and other variants of interest. …

Emerging SARS-CoV-2 variants and impact in global vaccination programs against SARS-CoV-2/COVID-19

CE Gómez, B Perdiguero, M Esteban - Vaccines, 2021 - mdpi.com
… the variants spread dominantly. In this review, we describe the different SARS-CoV-2 variants
… of the need to experimentally establish assays that determine to what extent the various …

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

NL Welch, M Zhu, C Hua, J Weller, ME Mirhashemi… - Nature medicine, 2022 - nature.com
… analysis, we evaluated RVP specificity experimentally. We … generation for each new
SARS-CoV-2 mutation or variant. Thus, we … of interest in the Spike gene in preparation for …

Emerging SARS-CoV-2 variants of concern (VOCs): an impending global crisis

AYK Thye, JWF Law, P Pusparajah, V Letchumanan… - Biomedicines, 2021 - mdpi.com
… to as the Alpha variant, was first detected in England on 20 … Mutations that are of interest and
that will be discussed in … by mutation at E484, many experiments showed that it reduces the …

A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution

T Zhang, R Deng, Y Wang, C Wu, K Zhang… - Nature Biomedical …, 2022 - nature.com
… mutations of interest in the SARS-CoV-2 genome (Fig. 4c). … customized to detect emerging
SARS-CoV-2 variants within … Thus, further experimental optimization by tuning the forward …

SARS-CoV-2: evolution and emergence of new viral variants

VR Flores-Vega, JV Monroy-Molina… - Viruses, 2022 - mdpi.com
new variants of SARS-CoV-2, which are classified as variants of concern (VOCs) and variants
of interest (… During in vitro experiments, the sera from immunized individuals with the Pfizer-…

Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants

J Arizti-Sanz, AD Bradley, YB Zhang… - Nature biomedical …, 2022 - nature.com
… conducted a month-long experiment to determine the stability of … for publication, a new
SARS-CoV-2 VOC arose (Omicron) … contains SNPs of interest in several SARS-CoV-2 VOCs, was …