Switching antidepressants in the treatment of major depression: when, how and what to switch to?

P Boyce, M Hopwood, G Morris, A Hamilton… - Journal of affective …, 2020 - Elsevier
… The aim of this paper is to review the evidence regarding when to switch antidepressants and
Early switching strategies in antidepressant non-responders: current evidence and future

[PDF][PDF] rTMS as a next step in antidepressant non-responders: a randomized comparison with current antidepressant treatment approaches

I Dalhuisen, I van Oostrom, J Spijker… - rTMS AS A … - repository.ubn.ru.nl
… In conclusion, rTMS should be considered as a viable treatment option at an early stage of
the treatment algorithm and may be more effective than antidepressant medication switch or …

[HTML][HTML] Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a …

GI Papakostas, MH Trivedi, RC Shelton… - Molecular …, 2024 - nature.com
… -approved augmentation versus switch strategies to employ. Our … The present study is the
first randomized effectiveness study to … Future studies comparing rTMS augmentation with other …

[HTML][HTML] Optimization versus early Switching in monopolar depression: A comprehensive review of a clinical controversy

R Correa, R Philippi - Rev. Chil. Neuropsiquiatr, 2019 - journalofneuropsychiatry.cl
… , switching will make clinical sense when early improvements … of antidepressant, other than
the one used in the first instance, … avoid abandoning treatments and therefore future relapses. …

Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder

O Köhler-Forsberg, ER Larsen… - The British Journal of …, 2019 - cambridge.org
early non-responders to sertraline (≤20% reduction in MADRS within the first 2 weeks),
randomisation to paroxetine switching (n =… Future trials may investigate mechanisms potentially …

Changes in antidepressant therapy should be considered early in patients with inadequate response to a first-line agent

BT Baune, P Falkai - Australian & New Zealand Journal of …, 2021 - journals.sagepub.com
… An open-label study in 192 patients without improvement after 2 weeks of initial escitalopram
compared a two-step early change/augmentation strategy (non-responders 4 weeks after …

Switching antidepressants in patients with treatment-resistant depression

D Souery, W Pitchot - Managing Treatment-Resistant Depression, 2022 - Elsevier
… reviewing the evidence (… early switching strategies) for the predictive value of early
improvement at 2–4 weeks to predict final antidepressant response concluded that lack of early

Combination Therapies and Switching of Agents in Depression and Bipolar Disorders

T Folsche, HB Maier, T Hillemacher… - …, 2021 - Springer
… This article aims to summarize the current evidence-based treatment options concerning …
Early switching strategies in antidepressant non-responders: current evidence and future

The use of sequential pharmacotherapy for the treatment of acute major depression: a scoping review

BDM Jones, MI Husain, BH Mulsant - Expert Opinion on …, 2021 - Taylor & Francis
… support for other strategies such as combining or switching antidepressants. In the future,
more studies … First, we review the evidence for four individual options: increasing AD dosage, …

Predictors of response to augmentation treatment in patients with treatment-resistant depression: a systematic review

RW Taylor, L Marwood, B Greer… - Journal of …, 2019 - journals.sagepub.com
… This review highlights the importance of early response as a … one antidepressant treatment
failure in their current depressive … discussed, we propose that future work should focus on the …