… , showed comparable efficacy outcomes including change from … Further controlled studies
are warranted to substantiate … -3, 11 a first-of-its-kind, 4-week, double-blind, phase 3 study of …

… We considered a mean change of 10.0 in HDRS compared to the … analysis after completing
the 12th-week visits for the first 48 … , we carried out the post-hoc analysis. It indicated that the …

… least two conventional monoaminergic antidepressant trials in … :19.3%, lithium/augmentation:18.9%,
nortriptyline/switching:21.5… evaluation within the context of broader clinical studies. …

… : (1) placebo-controlled trials with relevant long-term … pressants efficacy as post-hoc analyses
have found consistent … because aADM responders were not switched to PLA, excluding …

… The first cohort consists of subjects who underwent intravenous … Patients undergoing a
medication taper or change for KET-IV … at least two conventional antidepressant trials at optimal …

… Change from baseline was analyzed using mixed-effects … assess the data from this first
large clinical trial of TRD in the … Mood was assessed during regular treatment over the course …

… In this study, we monitored patient adherence through regular physical … , previous studies
have shown that early improvement in symptoms during the first two weeks of antidepressant …

… Therefore, we aimed to verify self-reported early sleep … A clinical trial also found that
the variation of sleep predicted … are associated with the change of depressive symptoms. …

… test to analyse ordinal variables (in our case, AEMS groups that were stratified over a continuum
from individuals without any mood switch to early … limitations of post-hoc analysis. A set …

… group were used from studies appearing more than once (ie, multi-arm trials). Numbers …
group was compared with several antidepressant groups in multi-arm trials. There are no years …