… CYP3A5 does not affect the pharmacokinetic variability of amlodipine [22… ABCB1 gene (also
known as multi drug resistance 1; MDR1) … The haplotype analysis data suggested that SNPs …

… is essential for comprehending drug pharmacokinetics and optimizing pharmacotherapy …
also determined the effect of polymorphisms C3435T, G2677T, C1236T of the MDR1 gene on …

… The expression of this protein determines the pharmacokinetics of drugs and, at one time, …
also determined the effect of polymorphisms C3435T, G2677T, C1236T of the MDR1 gene on …

… by the MDR1 gene, which provides the pharmacokinetics of … conducted worldwide to study
the effect of such genes on the … our results and the data obtained by the standardized test …

… It has a marked long duration of action where its elimination half-life ranges from 35 to 45 h
[… Similarly the deduced pharmacokinetic parameters of HCT came in close agreement with …

… effects at the cellular level related to xenobiotics, including drugs, are caused by their reactive
metabolites derived … and interethnic variation, whose CGC haplotype (1236/2677/3435) is …

… /zero/1.0/) applies to the data made available in this article, unless otherwise … Effect of
ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine …

… the efflux of amlodipine is multidrug resistance 1 (MDR1) and … The effects of multiple doses
of amlodipine/valsartan on the … 48- and 72-h visits were made for pharmacokinetic sampling. …

… Since P-gp affects the absorption and metabolism of drugs, the ABCB1 gene … Effect of
ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine …

… The ABCB1 gene of the antihypertensive drug amlodipine … cause differences in
pharmacokinetics, efficacy, and side effects. It … : Informed written consent was obtained from the …