Human genetic susceptibility to hepatitis B virus infection

J Xu, Q Zhan, Y Fan, Y Yu, Z Zeng - Infection, Genetics and Evolution, 2021 - Elsevier
… of HBV infection, namely chronic (persistent) HBV infection and … , including mutations in
human leukocyte antigens (HLAs), … related to the human susceptibility to HBV infection. Among …

[HTML][HTML] Association among cytokine profiles of innate and adaptive immune responses and clinical-virological features in untreated patients with chronic hepatitis B

Y Gu, Y Lian, Q Zheng, Z Huang, L Gu, Y Bi, J Li… - BMC Infectious …, 2020 - Springer
… the absence of an association regarding IFN-γ-secreting … effect to produce antiviral cytokines.
The detailed analysis of the noncytolytic control of viral infection derived from CHB patients

[HTML][HTML] … augments hepatitis B surface antigen clearance vs continuous nucleos (t) ide analog monotherapy in Chinese patients with chronic hepatitis B and hepatitis B …

FP Wu, Y Yang, M Li, YX Liu, YP Li… - World Journal of …, 2020 - ncbi.nlm.nih.gov
chronic hepatitis B patients with hepatitis B surface antigen levels ≤ 1500 IU/mL, hepatitis B
e antigen-negative and hepatitis B virus-… on the management of hepatitis B virus infection. J …

[HTML][HTML] Review of current and potential treatments for chronic hepatitis B virus infection

E Tsai - Gastroenterology & Hepatology, 2021 - ncbi.nlm.nih.gov
… : Chronic hepatitis B virus (HBV) infection remains a major global health burden. Millions of
people are at risk for complications of chronic HBV infection… for HBV infectioninterferon and …

Changes in the cytokine profiles of patients with chronic hepatitis B during antiviral therapy

MH Li, HH Lu, QQ Chen, YJ Lin, Z Zhan, LU Yao… - Biomedical and …, 2021 - Elsevier
Interferon can not only play a direct role in viral replication but also stimulate immune cell …
virusinfected liver cells. NA mainly inhibits viral replication and has no immunostimulatory effect

Hepatitis B virus infection and extra-hepatic manifestations: a systemic disease

P Cacoub, T Asselah - Official journal of the American College of …, 2022 - journals.lww.com
People living with hepatitis B virus (HBV) chronic infection are exposed to high rates of liver
complications including end-stage liver disease and hepatocellular carcinoma. Extrahepatic …

Interleukin 21 Reinvigorates the Antiviral Activity of Hepatitis B Virus (HBV)–Specific CD8+ T Cells in Chronic HBV Infection

L Tang, C Chen, X Gao, W Zhang, X Yan… - … Journal of Infectious …, 2019 - academic.oup.com
… role of IL-21 in promoting and sustaining CD8 + T-cell responses in the context of chronic
viral infection. … C, PBMCs from human leukocyte antigen A2+ patients with chronic HBV …

[HTML][HTML] Anti-viral effect in chronic hepatitis B patients with normal or mildly elevated alanine aminotransferase

Q Zhao, K Liu, X Zhu, L Yan, Y Ding, Y Xu, S Lou… - Antiviral Research, 2020 - Elsevier
… In our current study, PEG-IFN treated CHB patients had … that the CHB patients treated with
PEG-IFN who had elevated ALT … ) than overall mean HBsAg decline in entire PEG-IFN group. …

[HTML][HTML] Immune suppression in chronic hepatitis B infection associated liver disease: A review

TY Li, Y Yang, G Zhou, ZK Tu - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
… death ligand 1 (PD-L1) and human leukocyte antigen (HLA)-E] expressed in monocytes
in … response in patients with chronic hepatitis B virus infection. Hepatology. 2005;41:771–778. …

[HTML][HTML] Immune mechanisms underlying hepatitis b surface antigen seroclearance in chronic hepatitis b patients with viral coinfection

S Wu, W Yi, Y Gao, W Deng, X Bi, Y Lin… - Frontiers in …, 2022 - frontiersin.org
chronic hepatitis B virus infection, the human body may also be coinfected with other
hepatophilic or non-hepatophilic viruses… HCV infected hepatocytes through human leukocyte