… Therefore, in the current study, both the elevation in serum osmolality that reduces brain
water content and the amount of saline subsequently administered in response to the osmotic …

… in extracellular osmolarity by mannitol mediates the efflux of [Cl − ] i and water through CCCs…
post-hoc test between furosemide and furosemide + mannitol). These observations indicate …

… plasma osmolality, resulting in a greater reduction of brain … that adding furosemide to the
lowest mannitol dose as a brain-… findings regarding electrolytes and fluid balance and perfusion …

… study the effect of consecutive use of both drugs on the brain … brain water to the intravascular
compartment leading to brain … the administration of 20 mg furosemide in 18 (20%) patients; …

… Furosemide, a loop diuretic, inhibits sodium and water … pressure and enhancing plasma
osmolarity. It is metabolized … with mannitol and furosemide enhances cerebral circulation …

… or a serum osmolarity higher than 320 mOsm/L, mannitol infusion … of action has been attributed
to reducing brain water content … Concomitant use of furosemide can mitigate this risk [14]. …

… for therapy to increase serum osmolality. For this physiological … osmolality and draw normal
fluid from low osmolar brain … of mannitol with furosemide will have a synergistic effect in …

… mannitol’s effects on outcomes, including ICP, cerebral … MAP), brain relaxation, fluid intake,
urine output, and serum sodium. … changes to serum osmolality by free water and sodium loss. …

… plasma osmolality by intravenous infusion of mannitol or … decrease in brain water content
when furosemide was added to … seen when furosemide was added to treatment with mannitol. …

… The effect of furosemide on ICP is synergistic with mannitol. In a study performed on rats, …
Effect of mannitol and furosemide on plasma osmolality and brain water. Anesthesiology 96: …