Overview of biological effects of melatonin on testis: A review

S Heidarizadi, Z Rashidi, C Jalili, M Gholami - Andrologia, 2022 - Wiley Online Library
… toxicity, improve sperm quality and it affects the testosterone … effects of melatonin as a natural
antioxidant on testicles and … mice that were treated with melatonin had a testicular tissue …

Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats

H Eren, T Mercantepe, L Tumkaya… - Experimental and …, 2020 - Elsevier
… cisplatin was used to induce testis tissue damage, and amifostine and melatonin were used
as … We observed that treatment with amifostine, melatonin and amifostine plus melatonin

Protective effect of melatonin on alleviating early oxidative stress induced by DOX in mice spermatogenesis and sperm quality maintaining

T Zi, YN Liu, YS Zhang, ZL Wang, ZX Wang… - Reproductive Biology …, 2022 - Springer
… Many studies have attempted to protect against DOX-induced testicular toxicity, with
mixed results [17, 18]. Melatonin (MLT) is a promising antioxidant agent with a variety of …

Cardioprotective effect of melatonin and agomelatine on doxorubicin-induced cardiotoxicity in a rat model: an electrocardiographic, scintigraphic and biochemical …

H Aygun, SS Gul - Bratislava Medical Journal/Bratislavské …, 2019 - search.ebscohost.com
… demonstrated to protect brain in cerebral ischemia-reperfusion injury and
pentylenetetrazole-induced kindling epilepsy in rats, reduce testicular damage in STZ-induced Type I …

Melatonin as an adjuvant treatment modality with doxorubicin

PM Dana, F Sadoughi, RJ Reiter, S Mohammadi… - Biochimie, 2022 - Elsevier
… of AMPK, abolishes the mentioned effects [57]. In rats treated with melatonin and Dox, cardiac
… MLT suppressed Dox-induced testicular histopathological toxicity but did not reverse the …

Effects of quercetin against doxorubicin-induced testicular toxicity in male rats

Ö Güleş, G Doğan, UH Ercins, Ü Eren - Biology Bulletin, 2022 - Springer
… study investigated the protective effects of quercetin (QUE) in doxorubicin (DOX)-induced
to investigate the detailed effects of QUE against DOX-induced testicular toxicity in male rats. …

The role of melatonin on doxorubicin-induced cardiotoxicity: a systematic review

M Najafi, MRH Shayesteh, K Mortezaee, B Farhood… - Life sciences, 2020 - Elsevier
… was reported in the rats treated with doxorubicin compared to the control rats; the survival …
the other rats [14,15]. When both melatonin and doxorubicin was administered to the rats/mice, …

Treatment with melatonin and selenium attenuates docetaxel‐induced apoptosis and oxidative injury in kidney and testes of mice

E Baş, M Nazıroğlu - Andrologia, 2019 - Wiley Online Library
… and testes. We aimed to investigate potential modulatory roles … melatonin (MEL) and
selenium (Se) against DTX-induced apoptosis and oxidative injury in the testes and kidney of mice. …

The therapeutic effect of hesperetin on doxorubicin-induced testicular toxicity: Potential roles of the mechanistic target of rapamycin kinase (mTOR) and dynamin …

A Tektemur, NK Tektemur, EE Güzel - Toxicology and Applied …, 2022 - Elsevier
… as testicular damage markers, were analyzed in rat testis tissue samples. In addition, to
evaluate the potential presence of autophagy in this process, beclin 1 (BECN1), and autophagy-…

The role of toll-like receptors in the protective effect of melatonin against doxorubicin-induced pancreatic beta cell toxicity

E Taskin, C Guven, ST Kaya, L Sahin, S Kocahan… - Life sciences, 2019 - Elsevier
testis. The aim of current study is to investigate whether melatonin would be protective in
doxorubicin-induced … apoptosis in both H9c2 cells and mice [36]. Consistent with the mentioned …