[HTML][HTML] Targeting growth hormone function: strategies and therapeutic applications
M Lu, JU Flanagan, RJ Langley, MP Hay… - Signal transduction and …, 2019 - nature.com
… prolactin receptor in target tissues such as liver, muscle, bone, and adipose tissue (Fig. 1). It
is … an epitope on porcine GH and investigated the inhibitory effects on GH signaling and cell …
is … an epitope on porcine GH and investigated the inhibitory effects on GH signaling and cell …
[HTML][HTML] Implications of insulin-like growth factor-1 in skeletal muscle and various diseases
… such as muscle, heart, adipose tissue, brain… people and potentially in individuals with
neurodegenerative disorders [93]. IGF-1 has a progressively more powerful trophic impact than GH …
neurodegenerative disorders [93]. IGF-1 has a progressively more powerful trophic impact than GH …
[HTML][HTML] Effects of testosterone supplementation on body composition and lower-body muscle function during severe exercise-and diet-induced energy deficit: A proof …
SM Pasiakos, CE Berryman, JP Karl, HR Lieberman… - …, 2019 - thelancet.com
… body muscle function in non-obese males exposed to those military-relevant stressors. The
purpose of this study was to evaluate the effects … anabolic steroid, human growth hormone, or …
purpose of this study was to evaluate the effects … anabolic steroid, human growth hormone, or …
Physiological effect of ghrelin on body systems
… In this review, we found/confirmed that ghrelin has effect on … of fuel while sparing fat; inhibits
lipid oxidation and promotes … effects on muscle strength and energy metabolism via a GH-…
lipid oxidation and promotes … effects on muscle strength and energy metabolism via a GH-…
Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans
S Sachs, S Zarini, DE Kahn… - American Journal …, 2019 - journals.physiology.org
… It would have been ideal to measure stimulated IMAT lipolysis to evaluate the potential
impact on muscle lipid delivery. Unfortunately, fresh tissue was not available for these …
impact on muscle lipid delivery. Unfortunately, fresh tissue was not available for these …
Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes
RCR Meex, EE Blaak, LJC van Loon - Obesity Reviews, 2019 - Wiley Online Library
… of increased adipose tissue mass and muscle … of obese subcutaneous adipose tissue did
not impair myogenesis of young myoblasts,71 suggesting that the effect of obesity on muscle …
not impair myogenesis of young myoblasts,71 suggesting that the effect of obesity on muscle …
[HTML][HTML] A review of the effects of glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors on lean body mass in humans
… be attributed solely to fat mass (FM). Given the importance of skeletal muscle and lean body
… , we reviewed the available literature reporting the effects of GLP-1RAs and SGLT2is on …
… , we reviewed the available literature reporting the effects of GLP-1RAs and SGLT2is on …
[HTML][HTML] Temporal and masseter muscle evaluation by MRI provides information on muscle mass and quality in acromegaly patients
F Gatto, A Milioto, G Corica, F Nista, C Campana… - Pituitary, 2024 - Springer
… The impact of GH/IGF-1 levels on skeletal muscle in acromegaly is still … in GH and IGF-1
levels [10, 14]. In our cohort we observed that age was the main determinant of muscle fat …
levels [10, 14]. In our cohort we observed that age was the main determinant of muscle fat …
Growth hormone and insulin-like growth factor 1 regulation of nonalcoholic fatty liver disease
LE Dichtel, J Cordoba-Chacon… - The Journal of Clinical …, 2022 - academic.oup.com
… (7), “the effects of GH on substrate metabolism in humans are simple: during conditions
of … that the acute anti-insulin effects of GH on skeletal muscle are not due to impairment of …
of … that the acute anti-insulin effects of GH on skeletal muscle are not due to impairment of …
[HTML][HTML] Obesity alters the muscle protein synthetic response to nutrition and exercise
… the impact of protein ingestion and exercise on muscle protein remodeling in people with …
It is worthwhile noting that intramyocellular lipid accumulation in obese human muscle (60) …
It is worthwhile noting that intramyocellular lipid accumulation in obese human muscle (60) …