Relationship of IGF-1 and IGF-binding proteins to disease severity and glycemia in nonalcoholic fatty liver disease

TL Stanley, LT Fourman, I Zheng… - The Journal of …, 2021 - academic.oup.com
GH and IGF-1 have divergent effects on glycemia, with GH acting as a counterregulatory
hormone and IGF-1 exerting hypoglycemic effects, … and stimulate muscle glycogen synthesis are …

Effects of upper-body, lower-body, or combined resistance training on the ratio of follistatin and myostatin in middle-aged men

R Bagheri, A Rashidlamir, MS Motevalli… - European journal of …, 2019 - Springer
… RT increases skeletal muscle mass and decreases fat mass … The key finding we report is that
the greatest effects in the … to the different volume of muscles recruited in our RT programs. In …

[HTML][HTML] Growth hormone improves nerve regeneration, muscle re-innervation, and functional outcomes after chronic denervation injury

J Lopez, A Quan, J Budihardjo, S Xiang, H Wang… - Scientific reports, 2019 - nature.com
… In our study, we aimed to isolate the effects of GH on chronically denervated SCs by using
a model in which the sciatic nerve is transected and left in discontinuity for 8 weeks. We then …

Role of hormones in sarcopenia

T Priego, AI Martín, D González-Hedström… - Vitamins and …, 2021 - Elsevier
muscle stretch, a direct effect of GH on muscle stretch and function is not clear. The lack of
effect of GH treatment on muscle … The increase in intracellular muscle fat contributes to insulin …

Effects of hormonal changes on sarcopenia in chronic kidney disease: where are we now and what can we do?

O Gungor, S Ulu, NB Hasbal, SD Anker… - … and muscle, 2021 - Wiley Online Library
GH and IGF-1 levels. Studies also suggest that the GH/IGF-1 axis increases muscle mass
but has no effect … weight, total bod fat, and C-reactive protein levels in the hGH group were …

[HTML][HTML] Adiponectin and its mimics on skeletal muscle: insulin sensitizers, fat burners, exercise mimickers, muscling pills… or everything together?

M Abou-Samra, CM Selvais, N Dubuisson… - International journal of …, 2020 - mdpi.com
… its effects and mechanisms of action, first in healthy skeletal muscle including exercised
muscle, … We will focus on chronic exercise training and its effects on circulating ApN and muscle

Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver

GH Goossens, JWE Jocken, EE Blaak - Nature Reviews Endocrinology, 2021 - nature.com
… in humans, as well as the underlying mechanisms, and addresses the effect of these sex
differences on cardiometabolic health. Additionally, this Review highlights the implications of …

Actions and potential therapeutic applications of growth hormone–releasing hormone agonists

AV Schally, X Zhang, R Cai, JM Hare, R Granata… - …, 2019 - academic.oup.com
… As GHRH might function as a growth factor, we examined effects of GHRH agonists on …
resistance occurring primarily within the muscles, liver, and fat tissue. The proportion between …

Muscle–organ crosstalk: the emerging roles of myokines

MCK Severinsen, BK Pedersen - Endocrine reviews, 2020 - academic.oup.com
… The fact that white adipose tissue can shift into a brown-like phenotype, the discovery of
brown fat in humans, and the potentially beneficial effects of these depots have stimulated a …

[HTML][HTML] Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

R Sartori, V Romanello, M Sandri - Nature communications, 2021 - nature.com
muscle is the protein reservoir of our body and an important regulator of glucose and lipid
is synthesized predominately in the liver under the growth hormone (GH) action and acts as a …