[HTML][HTML] Hepatic growth hormone-JAK2-STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression

D Kaltenecker, M Themanns, KM Mueller, K Spirk… - Cytokine, 2019 - Elsevier
… In this review, we focus on the consequences of altered GH - JAK2 - STAT5 signaling for
hepatic lipid … It has several target tissues including the liver, muscle, bone and adipose tissue. …

[HTML][HTML] Regulation of postabsorptive and postprandial glucose metabolism by insulin-dependent and insulin-independent mechanisms: an integrative approach

GD Dimitriadis, E Maratou, A Kountouri, M Board… - Nutrients, 2021 - mdpi.com
adipose tissue and supply of glycerol and NEFA to the liver [30]. These effects of growth
hormone … synthesis in primary human muscle cells incubated in the presence of high (360 mg/dL…

[PDF][PDF] Mechanism of action and the effect of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on different types of physical performance-A systematic review

P Kaczka, MM Michalczyk, R Jastrząb… - Journal of human …, 2019 - sciendo.com
… the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and enhancement of muscle
… , where changes in strength, body fat and muscle mass as well as anaerobic performance …

Determinants of maternal insulin resistance during pregnancy: an updated overview

U Kampmann, S Knorr, J Fuglsang… - Journal of diabetes …, 2019 - Wiley Online Library
… Skeletal muscle and adipose tissue together represent the … free fatty acids is consequently
due to an attenuated effect of … same diabetogenic effects as pituitary growth hormone such as …

Hepatic sexual dimorphism—implications for non-alcoholic fatty liver disease

P Lefebvre, B Staels - Nature Reviews Endocrinology, 2021 - nature.com
… We note that STAT5a participates in GH-mediated signalling … , adipose tissue, immune cells
and skeletal muscle) also has … in visceral adipose tissue and exert tempering effects in NASH …

[HTML][HTML] The impact of keto-adaptation on exercise performance and the role of metabolic-regulating cytokines

M Sherrier, H Li - The American journal of clinical nutrition, 2019 - Elsevier
… necessary for enhancement in skeletal muscle fat and ketone oxidation after sustained …
impact on resting GH concentration (21), although the expected postexercise increase in GH

[HTML][HTML] Mechanisms underlying metabolic syndrome-related sarcopenia and possible therapeutic measures

ME Rubio-Ruiz, V Guarner-Lans… - International journal of …, 2019 - mdpi.com
… There is low leg muscle mass and a greater fat infiltration of fat in muscle fat in men than
in … [142] recently reported the effects of a GH-receptor analog that reduced fat mass and …

[HTML][HTML] Pancreatic cancer and cachexia—metabolic mechanisms and novel insights

KA Poulia, P Sarantis, D Antoniadou, E Koustas… - Nutrients, 2020 - mdpi.com
… is attributed both to muscle and fat mass loss. This is attributed to hyper catabolism of …
appetite-inducing effect and is also responsible for Growth Hormone stimulation and gastric motility …

[HTML][HTML] Molecular mechanism contributing to malnutrition and sarcopenia in patients with liver cirrhosis

F Meyer, K Bannert, M Wiese, S Esau… - International journal of …, 2020 - mdpi.com
… , increased myostatin and reduced human growth hormone. The concise … muscle mass,
bone mass and hemoglobin, and reduced fat mass and HbA1c [115]. Furthermore, effects of daily …

[HTML][HTML] Acromegaly, inflammation and cardiovascular disease: a review

TLC Wolters, MG Netea, NP Riksen… - Reviews in Endocrine …, 2020 - Springer
GH and IGF-1 have numerous effects on the immune and cardiovascular system. Since …
are associated with systemic inflammation and respond to GH/IGF-1 normalizing treatment. …