Hyperinsulinemia and its pivotal role in aging, obesity, type 2 diabetes, cardiovascular disease and cancer
JA Janssen - International journal of molecular sciences, 2021 - mdpi.com
… This insulin–GH shift promotes energy storage and lipid … effects, hyperinsulinemia will initially
result in excess fat … the development of insulin resistance in muscles and fat cells, the latter …
result in excess fat … the development of insulin resistance in muscles and fat cells, the latter …
[HTML][HTML] Insulin-like growth factors: Ligands, binding proteins, and receptors
… -I and 25% being derived from adipose and muscle [12]. In addition to GH, IGF-I production is
… concentration, the protective effects of IGF-I are secondary to overgrowth effects that lead to …
… concentration, the protective effects of IGF-I are secondary to overgrowth effects that lead to …
Osteosarcopenia: a narrative review on clinical studies
… In the muscle, fat can be located between muscle bundles as … effect of high-fat mass
highlights the importance of lean … reduced muscle sensitivity to GH with reduced muscle mass …
highlights the importance of lean … reduced muscle sensitivity to GH with reduced muscle mass …
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
AASLD Practice Guidance on the clinical assessment and manag... : Hepatology AASLD
Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver …
Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver …
Changes in lean body mass with glucagon‐like peptide‐1‐based therapies and mitigation strategies
IJ Neeland, J Linge… - Diabetes, Obesity and …, 2024 - Wiley Online Library
… increasing muscle mass is growth hormone (GH). Recombinant GH has been used in obesity
with low GH … Effect of liraglutide on thigh muscle fat and muscle composition in adults with …
with low GH … Effect of liraglutide on thigh muscle fat and muscle composition in adults with …
The combined effect of green tea and α-glucosyl hesperidin in preventing obesity: A randomized placebo-controlled clinical trial
R Yoshitomi, M Yamamoto, M Kumazoe, Y Fujimura… - Scientific reports, 2021 - nature.com
… level and body fat percentage decreased at week 12; body … -gH prevents weight gain, and
the antiobesity effect of GT-gH … , body fat percentage, BMI, lean body mass, and muscle mass, …
the antiobesity effect of GT-gH … , body fat percentage, BMI, lean body mass, and muscle mass, …
Sarcopenic obesity, insulin resistance, and their implications in cardiovascular and metabolic consequences
S Hong, KM Choi - International journal of molecular sciences, 2020 - mdpi.com
… Peri-muscular adipose tissue (PMAT) is an ectopic fat … Growth hormone (GH) is another
anabolic hormone that … has a protective effect for inflammation and lipid accumulation in skeletal …
anabolic hormone that … has a protective effect for inflammation and lipid accumulation in skeletal …
Circadian clocks and insulin resistance
DJ Stenvers, FAJL Scheer, P Schrauwen… - Nature Reviews …, 2019 - nature.com
… Insulin resistance in liver, muscle and adipose tissue is a pivotal … Thirdly, the diurnal
rhythm in growth hormone, which … These lifestyle changes have a substantial effect on the …
rhythm in growth hormone, which … These lifestyle changes have a substantial effect on the …
IGF-1 and cardiovascular disease
Y Higashi, S Gautam, P Delafontaine… - Growth Hormone & IGF …, 2019 - Elsevier
… (endothelial cells and smooth muscle cells). IGF-1 exerts a variety of effects on these cell types
… done at a 3-month time point of high-fat diet feeding, so potential effects of IGF-1 on early …
… done at a 3-month time point of high-fat diet feeding, so potential effects of IGF-1 on early …
[HTML][HTML] Growth hormone enhances the recovery of hypoglycemia via ventromedial hypothalamic neurons
IC Furigo, GO de Souza, PDS Teixeira… - The FASEB …, 2019 - ncbi.nlm.nih.gov
… GH receptor (GHR) in the liver, adipose tissue, and skeletal muscle, all well-known direct
GH-… , we hypothesized that the effects of GH on the CRR may require GH signaling in the brain …
GH-… , we hypothesized that the effects of GH on the CRR may require GH signaling in the brain …