The impact of amyloid-β or tau on cognitive change in the presence of severe cerebrovascular disease
…, Alzheimer's Disease Neuroimaging … - … Disease, 2020 - content.iospress.com
… We included 60 subcortical vascular cognitive impairment (… AD (remaining 121 subjects
with clinically normal cognition) … , the effects of Aβ positivity or tau burden on cognitive decline …
with clinically normal cognition) … , the effects of Aβ positivity or tau burden on cognitive decline …
Brain amyloid β, cerebral small vessel disease, and cognition: A memory clinic study
…, S Hilal, SG Villaraza, A Reilhac, B Gyanwali… - Neurology, 2020 - AAN Enterprises
… to individuals with subcortical vascular cognitive impairment. … although individuals with MCI
or AD had higher brain Aβ burden … MCI and AD with and without cerebrovascular disease. …
or AD had higher brain Aβ burden … MCI and AD with and without cerebrovascular disease. …
White matter abnormalities are key components of cerebrovascular disease impacting cognitive decline
P Vemuri, J Graff-Radford, TG Lesnick… - Brain …, 2021 - academic.oup.com
… 1089 individuals aged ≥60 years with concurrent amyloid-PET … Subcortical/cortical infarctions
and lobar/deep CMBs might … impact of PC3 would be on baseline cognition and not rate of …
and lobar/deep CMBs might … impact of PC3 would be on baseline cognition and not rate of …
Independent effect of Aβ burden on cognitive impairment in patients with small subcortical infarction
SH Kang, M Kang, JH Han, ES Lee, KJ Lee… - Alzheimer's Research & …, 2023 - Springer
… compare the clinical characteristics of the post-stroke normal cognition (PSNC) and PSCI
groups. … infarctions might be higher than that in normal elderly individuals. Several mechanisms …
groups. … infarctions might be higher than that in normal elderly individuals. Several mechanisms …
Influence of comorbidity of cerebrovascular disease and amyloid-β on Alzheimer's disease
… to measuring cerebrovascular disease burden, such as the … of our analyses may be subject
to inherent challenges with … of limiting the impact of cerebrovascular disease on cognition. …
to inherent challenges with … of limiting the impact of cerebrovascular disease on cognition. …
Vascular burden score impacts cognition independent of amyloid PET and MRI measures of Alzheimer's disease and vascular brain injury
…, P Maillard, D Harvey, B Singh… - … Disease, 2019 - content.iospress.com
… cognitive impairment. Using the previously reported PiB cutoff of 1.08 [12], we also found that
48% of all subjects were considered to have a high amyloid burden … cardiovascular disease …
48% of all subjects were considered to have a high amyloid burden … cardiovascular disease …
Amyloid and cerebrovascular burden divergently influence brain functional network changes over time
… Finally, instead of separating individuals into PiB+ and PiB− … the effects of Aβ and
cerebrovascular disease burden on … and examine how they might differentially affect cognition. …
cerebrovascular disease burden on … and examine how they might differentially affect cognition. …
Application of an amyloid and tau classification system in subcortical vascular cognitive impairment patients
… Aβ-positive (Aβ+) individuals could be grouped into the following … CSVD burden may have
an effect on cognitive impairment … Finally, we investigated the trajectories in cognition and MRI …
an effect on cognitive impairment … Finally, we investigated the trajectories in cognition and MRI …
Independent effects of amyloid and vascular markers on long‐term functional outcomes: An 8‐year longitudinal study of subcortical vascular cognitive impairment
SH Kang, S Woo, S Kim, JP Kim, H Jang… - European Journal of …, 2022 - Wiley Online Library
… individuals without dementia [32]. Therefore, it would be reasonable to expect that the effects
of … All participants in our SVCI cohort had severe CSVD burdens, which makes it difficult to …
of … All participants in our SVCI cohort had severe CSVD burdens, which makes it difficult to …
Complex profiles of cerebrovascular disease pathologies in the aging brain and their relationship with cognitive decline
… individual CVD neuropathologies and cognition, 7–17 we … -related plaque and tangle burden
28 were used to determine … in older community-dwelling individuals. Overall, mixed CVD …
28 were used to determine … in older community-dwelling individuals. Overall, mixed CVD …