Clinical associations of T2-weighted lesion load and lesion location in small vessel disease: insights from a large prospective cohort study

A Altermatt, L Gaetano, S Magon, L Bauer, R Feurer… - Neuroimage, 2019 - Elsevier
burden and cognitive impairment is observed. Indeed, some individuals may exhibit extensive
WM disease … adults (INtervention project on cerebroVAscular disease and Dementia in the …

Global burden of small vessel disease–related brain changes on MRI predicts cognitive and functional decline

…, S Melkas, T Nieminen, A Brander, A Korvenoja… - Stroke, 2020 - Am Heart Assoc
effects on cognition than those of the posterior regions. … for both cognitive and functional
outcome in older individuals with … of the individual cerebrovascular disease biomarkers. Global …

Vascular cognitive impairment

J Graff-Radford - Continuum: Lifelong Learning in Neurology, 2019 - journals.lww.com
… In individuals with mild vascular cognitive impairment, aerobic … In one study, increased
burden of basal ganglia perivascular … represents a spectrum of cerebrovascular diseases with …

Reduced fractional anisotropy of the genu of the corpus callosum as a cerebrovascular disease marker and predictor of longitudinal cognition in MCI

S Raghavan, SA Przybelski, RI Reid… - Neurobiology of …, 2020 - Elsevier
… dementia from MCI is not explained by brain amyloid beta levels, there is a need for … cognitive
decline in individuals with MCI over 60 years of age in conjunction with brain amyloidosis

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

A Montagne, DA Nation, AP Sagare, G Barisano… - Nature, 2020 - nature.com
… and informant; history of cardiovascular disease (heart failure, … We assigned an elevated
VRF burden to individuals with two or … function and language) and one test of global cognition. …

Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline

JS Rabin, E Nichols, R La Joie, KB Casaletto, P Palta… - Brain, 2022 - academic.oup.com
cerebrovascular disease contributes to Alzheimer’s disease … We included data from autopsied
subjects recruited from one of … on cognitive decline (that was not mediated by tau burden) …

[PDF][PDF] An assessment of the relationship between structural and functional imaging of cerebrovascular disease and cognition-related fibers

…, X Xiao, J Yin, T Yang, B Zeng - … Methods in Medicine, 2020 - downloads.hindawi.com
… between cerebrovascular disease and cognitive impairment [4]. … Effects of cerebrovascular
disease and amyloid beta burden on cognition in subjects with subcortical vascular cognitive

Effect of physical activity on cognitive impairment in patients with cerebrovascular diseases: A systematic review and meta-analysis

H Lin, HH Liu, Y Dai, X Yin, Z Li, L Yang, J Tao… - Frontiers in …, 2022 - frontiersin.org
… ) on cognition in patients with cerebrovascular disease and … and cognitive dysfunction, which
brings a great burden to the … : (1) subjects with the cerebrovascular disorder were confirmed …

Role of white matter hyperintensities and related risk factors in vascular cognitive impairment: a review

Y Chen, X Wang, L Guan, Y Wang - Biomolecules, 2021 - mdpi.com
… and in the cerebrospinal fluid levels of amyloid beta (Aβ 40/42 ) [… amyloid burden and WMH
in cases of worsening cognition [… in elderly individuals with a silent cerebral vascular disease, …

[HTML][HTML] Altered neurovascular coupling in patients with vascular cognitive impairment: a combined ASL-fMRI analysis

Z Ruan, D Sun, X Zhou, M Yu, S Li, W Sun… - Frontiers in Aging …, 2023 - ncbi.nlm.nih.gov
… is WML burden, the dependent variable is global cognition, and … Specifically, compared to
the subjects in the HCs group, those … to cerebrovascular disease, which can lead to cognitive