Vascular calcification maladaptively participates in acute phosphate homeostasis

ME Turner, TS Rowsell, AP Lansing… - Cardiovascular …, 2023 - academic.oup.com
chronic kidney disease (CKD), where exposure to increased … and phosphate binder therapy
is prevalent in CKD patients, … have shown its most dramatic effect is on the progression of pre…

Chronic Kidney Disease–Mineral and Bone Disorders

IA Portales-Castillo, EW Yu, H Jüppner… - … Chronic Kidney Disease …, 2022 - Springer
… explaining why even patients with early-stage CKD have lower … -containing binders,
especially in patients with elevated … -target effects and costs of specific phosphate binders should …

[HTML][HTML] Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease

N Fountoulakis, PM Psefteli, G Maltese, L Gnudi… - Kidney International …, 2023 - Elsevier
… In the early stages of chronic kidney disease (CKD), there is … were no patients receiving
vitamin D, phosphate binders, or … In our cohort in people with diabetes and early stage CKD the …

[HTML][HTML] Diagnosis and Management of Chronic Kidney Disease-Mineral Bone Disease in Children

JS Suh - Childhood Kidney Diseases, 2020 - chikd.org
Patients with early-stage CKD who present with disordered … increased to monitor treatment
efficacy and side effects. The … Phosphate binders in combination with dietary phosphorus

[HTML][HTML] … in the chronic kidney disease-mineral bone disorder show the role of osteocytic proteins, a potential mechanism of the bone—Vascular paradox, a therapeutic …

MJ Williams, SC White, Z Joseph, KA Hruska - Frontiers in Physiology, 2023 - frontiersin.org
… is an early stage of cardiovascular disease leading to high … been implicated in vascular
calcification, although the effects are … use of calcium-containing phosphate binders, can result in …

Executive summary: clinical practice guideline of chronic kidney disease–mineral and bone disorder (CKD-MBD) in China

, … Clinical Research Center for Kidney Disease - … Diseases, 2019 - karger.com
… monitor for trends, treatment efficacy and side effects. 2.1.3 For … the dose of calcium-containing
phosphate binders. (2B) 3.3.3 … At the early stage of renal transplantation, we recommend …

Dual inhibition of gastrointestinal phosphate absorption: more questions than answers

WCG Yeung, ND Toussaint… - Journal of the American …, 2019 - journals.lww.com
… and noncalcium phosphate binders are limited by gastrointestinal side effects, increased …
Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease

Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk factor?

L Pickup, A Radhakrishnan, JN Townend… - … in nephrology and …, 2019 - journals.lww.com
… into the vascular effects of phosphate binders in CKD is … aortic PWV in the Chronic Renal
Insufficiency Cohort. This study … of arterial stiffness in patients with chronic kidney disease (CKD…

Research Progress on Mineral and Bone Metabolism Disorders in Chronic Kidney Disease

W Wang, Y Wu, L Xu, H Li, Y Zhao - MEDS Clinical Medicine, 2022 - clausiuspress.com
… FGF-23 increases at the early stage of CKD, which affects … calcium phosphate binders, calcium
phosphate binders are … binding agent has the effect of preventing vascular calcification. A …

The Bone-Vascular Axis in Chronic Kidney Disease: From Pathophysiology to Treatment

C Vachey, A Candellier, S Toutain… - Current Osteoporosis …, 2024 - Springer
early stage of CKD and are inversely correlated with kidney … , the cardiovascular effects of
lowering phosphate levels in … phosphate binders are widely prescribed to CKD patients, the …