Flutamide-induced alterations in transcriptional profiling of neonatal porcine ovaries

K Knapczyk-Stwora, A Nynca, RE Ciereszko… - Journal of animal …, 2019 - Springer
… that flutamide affects expression of genes involved in oocyte fertilization in the pig. Such …
observed in rat oocytes in vitro exposed to 2-hydroxyflutamide [57]. However, further research is …

[PDF][PDF] Effects of vinclozolin exposure on the expression and activity of SIRT1 and SIRT6 in the porcine ovary.

G Gorczyca, K Wartalski, Z Tabarowski… - Journal of Physiology & …, 2019 - jpp.krakow.pl
… suggest that in the porcine ovary the augmentation of SIRT1 expression may be related …
Effects of testosterone and 2-hydroxyflutamide on progesterone receptor expression in porcine

The Molecular Quality and Mitochondrial Activity of Porcine Cumulus–Oocyte Complexes Are Affected by Their Exposure to Three Endocrine-Active Compounds …

G Gorczyca, K Wartalski, M Romek, M Samiec… - International Journal of …, 2022 - mdpi.com
… which encompass biochemical substances synthesized from testosterone or one of their
derivatives. Depending on the target tissue, AASs exhibit anabolic or androgenic effects [13,14]. …

Activation of Steroidogenesis, Anti-Apoptotic Activity, and Proliferation in Porcine Granulosa Cells by RUNX1 Is Negatively Regulated by H3K27me3 Transcriptional …

Y Zhong, L Li, Y He, B He, Z Li, Z Zhang, H Zhang… - Genes, 2020 - mdpi.com
… Decreased H3K27me3 stimulates the expression of … activity, but decreasing progesterone.
Both the complementary … significantly repressed but progesterone is markedly increased …

[HTML][HTML] Androgen receptors and sociosexual behaviors in mammals: The limits of generalization

A Ågmo - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
… secrete testosterone and the ovaries estrogen and progesterone, … of the receptor mediating
the effects of testosterone, this … In castrated guinea-pigs, implants of dihydrotestosterone into …

Androgens regulate follicle stage-dependent pro-and anti-apoptosis in teleost ovaries through ZIP9 activation of different G proteins

A Converse, P Thomas - Biology of reproduction, 2019 - academic.oup.com
… However, more recent in vitro studies in porcine and murine … progestin receptor α (mPRα)
and G protein-coupled estrogen … For examining the effects of testosterone on the expression

[HTML][HTML] Breaking androgen receptor addiction of prostate cancer by targeting different functional domains in the treatment of advanced disease

ZR Maylin, RCB Nicolescu, H Pandha, M Asim - Translational oncology, 2021 - Elsevier
receptor is also a factor to consider for treatment. Bicalutamide is known to have a low binding
affinity to the progesterone receptorprogesterone to androgen precursors of testosterone, …

[HTML][HTML] Wpływ hydroksyflutamidu (2-Hf) na rozmieszczenie receptora progesteronowego w hodowanych komórkach warstwy ziarnistej świni.

M Jastrzębska - 2020 - ruj.uj.edu.pl
Progesterone receptor is expressed in two isoforms, PGRA and PGRB, which have been …
pig follicles were cultured for 24 hours in the presence of testosterone (T), 2-hydroxyflutamide