Developmental conditions modulate DNA methylation at the glucocorticoid receptor gene with cascading effects on expression and corticosterone levels in zebra …
… modulate gene expression. In mammals, methylation of the glucocorticoid receptor gene
Nr3c1 has been implicated as mediator of long-term effects of developmental conditions, but …
Nr3c1 has been implicated as mediator of long-term effects of developmental conditions, but …
Aberrant epigenomic modulation of glucocorticoid receptor gene (NR3C1) in early life stress and major depressive disorder correlation: systematic review and …
L Holmes Jr, E Shutman, C Chinaka, K Deepika… - … of environmental …, 2019 - mdpi.com
… that the DNA methylation of the glucocorticoid receptor gene (… , dense DNA methylation of
the glucocorticoid receptor gene (… Addressing maternal stress, separation, and child abuse and …
the glucocorticoid receptor gene (… Addressing maternal stress, separation, and child abuse and …
Glucocorticoid receptor gene (NR3C1) methylation during the first thousand days: Environmental exposures and developmental outcomes
… This systematic review highlights the role played by the NR3C1 gene methylation in linking
early exposures to adverse events and protective care during the first 1000 days and the …
early exposures to adverse events and protective care during the first 1000 days and the …
Methylation of the glucocorticoid receptor promoter in children: Links with parents as teachers, early life stress, and behavior problems
ES Gardini, S Schaub, A Neuhauser… - Development and …, 2022 - cambridge.org
… effect of the early social environment on NR3C1 methylation … to confirm the effect of ELS
and social interventions on NR3C1 … on glucocorticoid receptor gene methylation: A systematic …
and social interventions on NR3C1 … on glucocorticoid receptor gene methylation: A systematic …
Epigenetic mechanisms of the glucocorticoid receptor
… Modification of specific residues govern GLP/G9a association with HP1γ and glucocorticoid
receptor (GR) at target genes. Site-specific methylation of GLP/G9a promotes association …
receptor (GR) at target genes. Site-specific methylation of GLP/G9a promotes association …
Effects of Early Life Stress on Epigenetic Changes of the Glucocorticoid Receptor 17 Promoter during Adulthood
MK Seo, S Kim, DH Seog, WM Bahk, SH Kim… - International Journal of …, 2020 - mdpi.com
… This indicates that environmental stress factors are … on DNA methylation rather than histone
modification [9,27]. The GR exon 1 7 promoter with the NGF1A binding site, DNA methylation …
modification [9,27]. The GR exon 1 7 promoter with the NGF1A binding site, DNA methylation …
Maternal Anxiety and Depression in Pregnancy and DNA Methylation of the NR3C1 Glucocorticoid Receptor Gene
AE Dereix, R Ledyard, AM Redhunt, TR Bloomquist… - …, 2021 - Taylor & Francis
… Hypermethylation of the promoter region of the glucocorticoid receptor gene, NR3C1, has
been … Cross-fostering studies in rodents have demonstrated a causal effect of early life stress, …
been … Cross-fostering studies in rodents have demonstrated a causal effect of early life stress, …
The role of glucocorticoid and mineralocorticoid receptor DNA methylation in antenatal depression and infant stress regulation
M Galbally, SJ Watson, M van IJzendoorn… - …, 2020 - Elsevier
… considerably on these findings for DNA methylation of NR3C2 in the context of maternal
depression and child cortisol by ensuring our findings have meaning within clinical disorders. …
depression and child cortisol by ensuring our findings have meaning within clinical disorders. …
Early-life social experience affects offspring DNA methylation and later life stress phenotype
… DNA methylation of the promoter region of the hippocampal glucocorticoid receptor (GR;
NR3C1) gene, … favorable early social environment is associated with a better stress phenotype …
NR3C1) gene, … favorable early social environment is associated with a better stress phenotype …
Glucocorticoid receptor gene (NR3C1) is hypermethylated in adult males with aggressive behaviour
L Liu, J Li, L Qing, M Yan, G Xiong, X Lian, L Hu… - International Journal of …, 2021 - Springer
… glucocorticoid receptor (GR, encoded by the NR3C1 gene) can exert negative feedback on
the HPA axis by binding to glucocorticoids … is the first to study NR3C1 gene methylation in the …
the HPA axis by binding to glucocorticoids … is the first to study NR3C1 gene methylation in the …