Efficacy and tolerability of desvenlafaxine in the real-world treatment of patients with major depression: a narrative review and an expert opinion paper

G Sampogna, F Caraci, C Carmassi… - Expert Opinion on …, 2023 - Taylor & Francis
… that inhibit NET only at higher dosages (150-225 mg/d) [Citation48]. A weak binding affinity
… in managing cognitive complaints associated with major depressive episode has also been …

Safety, tolerability, and efficacy of desvenlafaxine in children and adolescents with major depressive disorder: results from two open-label extension trials

S Atkinson, L Thurman, S Ramaker, G Buckley… - CNS …, 2019 - cambridge.org
safety and tolerability of desvenlafaxine for the treatment of children and adolescents with
Desvenlafaxine 20 to 50 mg/d was generally safe and well tolerated with no new safety

Desvenlafaxine in the treatment of major depression: an updated overview

TR Norman, JS Olver - Expert opinion on pharmacotherapy, 2021 - Taylor & Francis
… was an effective antidepressant with favorable safety and tolerability in adults. … The
present article considers additional trials of desvenlafaxine in major depressive disorder. …

[HTML][HTML] … , randomized, double-blind, duloxetine-controlled, non-inferiority trial of desvenlafaxine succinate extended-release in patients with major depressive disorder

Q Zhao, B Fu, N Lyu, X Xu, G Huang, Y Tan… - Journal of Affective …, 2023 - Elsevier
… of major depressive episodes (MDEs) and prior treatments between … safety profile of
desvenlafaxine XL in this study was similar to that in prior studies, without new safety or tolerability

… response and remission with desvenlafaxine 50 mg and 100 mg: a pooled analysis of randomized, placebo-controlled studies in patients with major depressive …

CN Soares, DB Wajsbrot, M Boucher - CNS spectrums, 2020 - cambridge.org
… Only data from placebo and desvenlafaxine 50- and 100-mg/d treatment arms were … efficacy
and tolerability of desvenlafaxine 10 and 50 mg/d in adult outpatients with major depressive

Efficacy, safety, and tolerability of ansofaxine (LY03005) extended-release tablet for major depressive disorder: a randomized, double-blind, placebo-controlled, dose …

W Mi, F Yang, H Li, X Xu, L Li, Q Tan… - International Journal …, 2022 - academic.oup.com
… for the treatment of major depressive disorder (MDD). … to desvenlafaxine in vivo, ansofaxine
and desvenlafaxine can … (40–160 mg/d) demonstrated its safety, efficacy, and tolerability in …

Effects of desvenlafaxine versus placebo on MDD symptom clusters: a pooled analysis

MA Katzman, X Wang, DB Wajsbrot… - Journal of …, 2020 - journals.sagepub.com
… Using data from nine double-blind, placebo-controlled studies of desvenlafaxine for the
treatment of major depressive disorder (N=4317), the effect of desvenlafaxine 50 or 100 mg …

Desvenlafaxine vs. placebo in the treatment of persistent depressive disorder

DJ Hellerstein, JW Stewart, Y Chen, V Arunagiri… - Journal of Affective …, 2019 - Elsevier
Tolerability was assessed at each visit by self-rated scales and clinician … 50 mg equivalent
and 18 taking 100 mg equivalent; active drug non-responders (n = 9) were all taking 100 mg/d

[HTML][HTML] Impact of polymorphisms in CYP and UGT enzymes and ABC and SLCO1B1 transporters on the pharmacokinetics and safety of desvenlafaxine

S Calleja, P Zubiaur, D Ochoa… - Frontiers in …, 2023 - frontiersin.org
… is one more drug in the therapeutic arsenal available to treat depression, and … tolerability
or effectiveness. We were also unable to analyze the influence of Black race on desvenlafaxine

[HTML][HTML] Head-to-head comparison of vortioxetine versus desvenlafaxine in patients with major depressive disorder with partial response to SSRI therapy: Results of …

RS McIntyre, I Florea, MM Pedersen… - The Journal of Clinical …, 2023 - psychiatrist.com
… To maintain the blind, desvenlafaxine dose adjustment could … for desvenlafaxine, there is
no evidence that doses > 50 mg/d … perceptions of treatment efficacy and tolerability and has …