Effectiveness and Safety of a Structured De-Escalation from Antipseudomonal Β-Lactams in Bloodstream Infections Due to Enterobacterales: A Multicentre …
LE López-Cortés, M Delgado-Valverde… - papers.ssrn.com
… Background: De-escalation from broad-spectrum to narrow-… The objective was to determine
whether de-escalation from … to one of the de-escalation options and treated empirically with …
whether de-escalation from … to one of the de-escalation options and treated empirically with …
Efficacy and safety of antimicrobial de-escalation as a clinical strategy
C Mathieu, B Pastene, N Cassir… - Expert review of anti …, 2019 - Taylor & Francis
… it does not have a consensual definition, de-escalation consists of … a six-rank, consensual
classification of β-lactams, but the … The development of a rapid diagnostic test may alleviate the …
classification of β-lactams, but the … The development of a rapid diagnostic test may alleviate the …
Assessing the ecological benefit of antibiotic de-escalation strategies to elaborate evidence-based recommendations
PL Woerther, F Barbier, R Lepeule… - Clinical Infectious …, 2020 - academic.oup.com
… For these reasons, we believe that both the consensus ranking of beta-lactams used [2]
and the positioning of other antibiotic classes, as proposed in this work, should be entirely …
and the positioning of other antibiotic classes, as proposed in this work, should be entirely …
Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label …
LE López-Cortés, M Delgado-Valverde… - The Lancet Infectious …, 2024 - thelancet.com
… a response adjusted for duration of antibiotic risk (RADAR), in which the duration of exposure
to antipseudomonal β-lactams was added as a tie-breaking variable for the DOOR rank. …
to antipseudomonal β-lactams was added as a tie-breaking variable for the DOOR rank. …
[HTML][HTML] Antimicrobial de-escalation in the ICU: from recommendations to level of evidence
… can be considered de-escalation is the ranking of the … expert consensus regarding the final
version of the definition. … treated with anti-pseudomonal β-lactams. They found no significant …
version of the definition. … treated with anti-pseudomonal β-lactams. They found no significant …
Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European …
… panel and updated until a consensus was reached. Questions were … Two studies have
ranked antibiotics to provide a classification … on the development of resistance to antimicrobials? …
ranked antibiotics to provide a classification … on the development of resistance to antimicrobials? …
[HTML][HTML] Antimicrobial de-escalation as part of antimicrobial stewardship in intensive care: no simple answers to simple questions—a viewpoint of experts
JJ De Waele, J Schouten, B Beovic, A Tabah… - Intensive care …, 2020 - Springer
… of those agents have little impact on the development of AMR. However, this … rank
consensual classification of beta-lactam antibiotics. Despite several Delphi rounds, no consensus …
consensual classification of beta-lactam antibiotics. Despite several Delphi rounds, no consensus …
Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium
… even de-escalation of the pivotal agent remains unclear, and there is no consensus relating
to the ranking … Two different groups made an attempt to obtain a relevant ranking based on a …
to the ranking … Two different groups made an attempt to obtain a relevant ranking based on a …
Antimicrobial stewardship programmes focused on de-escalation: a narrative review of efficacy and risks
H Umpleby, A Dushianthan, T Catton… - Journal of Emergency …, 2022 - eprints.soton.ac.uk
… of resistance development. Despite several Delphi rounds, they were unable to reach consensus
on … The ranking of antibiotics is considerably different between the two scoring systems, …
on … The ranking of antibiotics is considerably different between the two scoring systems, …
[PDF][PDF] Update in Antibiotic Therapy in Intensive Care Unit
… However, even de-escalation of the pivotal agent remains unclear. There is also no …
Elaboration of a consensual definition of de-escalation allowing a ranking of β-lactams. Clin …
Elaboration of a consensual definition of de-escalation allowing a ranking of β-lactams. Clin …